Adult neurogenesis in the hippocampus: A role in learning and memory

Elise C. Cope, Elizabeth Gould

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

While we have known for some time that new neurons are produced in the dentate gyrus of the hippocampus throughout adulthood, the role of adult neurogenesis in relation to known hippocampal functions, such as spatial navigation learning and memory, is still an area of active investigation. New neurons are highly sensitive to experience, and evidence suggests that environmental conditions that enhance neurogenesis also improve cognitive performance, whereas those that reduce neurogenesis have the opposite effect. More recently, adult hippocampal neurogenesis has been shown to be important for forming new representations by aiding in pattern separation, reducing interference, and promoting forgetting.

Original languageEnglish (US)
Title of host publicationThe Curated Reference Collection in Neuroscience and Biobehavioral Psychology
PublisherElsevier Science Ltd.
Pages345-358
Number of pages14
ISBN (Electronic)9780128093245
DOIs
StatePublished - Jan 1 2016

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Keywords

  • Adult neurogenesis
  • Context fear conditioning
  • Dentate gyrus
  • Forgetting
  • Granule cell
  • Interference
  • Pattern separation
  • Spatial navigation learning

Fingerprint Dive into the research topics of 'Adult neurogenesis in the hippocampus: A role in learning and memory'. Together they form a unique fingerprint.

  • Cite this

    Cope, E. C., & Gould, E. (2016). Adult neurogenesis in the hippocampus: A role in learning and memory. In The Curated Reference Collection in Neuroscience and Biobehavioral Psychology (pp. 345-358). Elsevier Science Ltd.. https://doi.org/10.1016/B978-0-12-809324-5.21115-2