Adenovirus type 5 virions can be assembled in vivo in the absence of detectable polypeptide IX

W. W. Colby, T. Shenk

Research output: Contribution to journalArticlepeer-review

81 Scopus citations

Abstract

Mutant dl313 is an adenovirus type 5 deletion mutant which lacks 2,307 base pairs, including the 5' portion of the polypeptide IX gene. Mutant virions did not contain detectable levels of this polypeptide. They were substantially more thermolabile than wild-type particles and did not produce hexon nonomers upon pyridine disruption.

Original languageEnglish (US)
Pages (from-to)977-980
Number of pages4
JournalJournal of virology
Volume39
Issue number3
DOIs
StatePublished - 1981

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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