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ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis
Xin Lu
, Qiongqing Wang
, Guohong Hu
, Catherine Van Poznak
, Martin Fleisher
, Michael Reiss
, Joan Massagué
,
Yibin Kang
Molecular Biology
Princeton Branch of the Ludwig Institute for Cancer Research
Research output
:
Contribution to journal
›
Article
›
peer-review
270
Scopus citations
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Dive into the research topics of 'ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis'. Together they form a unique fingerprint.
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Biochemistry, Genetics and Molecular Biology
Interstitial Collagenase
100%
ADAMTS1
100%
Thrombospondin
25%
Disintegrin
25%
Amphiregulin
25%
Heparin-Binding EGF-like Growth Factor
25%
Keyphrases
ADAMTS
100%
Matrix metalloproteinase-1 (MMP-1)
100%
Thrombospondin-1 (TSP-1)
25%
Amphiregulin
25%
Disintegrin
25%
HB-EGF
25%
Pharmacology, Toxicology and Pharmaceutical Science
Interstitial Collagenase
100%
ADAMTS Protein
16%
Epidermal Growth Factor Receptor Kinase Inhibitor
16%
Heparin Binding Epidermal Growth Factor
16%
Osteoprotegerin
16%
Amphiregulin
16%
Medicine and Dentistry
Interstitial Collagenase
100%
Heparin Binding Epidermal Growth Factor
16%
ADAMTS Protein
16%
Amphiregulin
16%
Cell Receptor
16%