TY - JOUR
T1 - Acute infection induces a metastatic niche
T2 - A double menace for cancer patients
AU - Smith, Heath A.
AU - Kang, Yibin
PY - 2013/9/1
Y1 - 2013/9/1
N2 - Tumor-derived factors can induce a premetastatic niche, yet little is known about how metastatic microenvironments are influenced by external insults, such as acute infections commonly seen in patients with cancer. New findings reveal increased metastasis to the lung after acute bacterial infection via the CXCR4/ubiquitin axis, suggesting new targets for antimetastasis therapeutics.
AB - Tumor-derived factors can induce a premetastatic niche, yet little is known about how metastatic microenvironments are influenced by external insults, such as acute infections commonly seen in patients with cancer. New findings reveal increased metastasis to the lung after acute bacterial infection via the CXCR4/ubiquitin axis, suggesting new targets for antimetastasis therapeutics.
UR - http://www.scopus.com/inward/record.url?scp=84883484949&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883484949&partnerID=8YFLogxK
U2 - 10.1158/1078-0432.CCR-13-1524
DO - 10.1158/1078-0432.CCR-13-1524
M3 - Article
C2 - 23922303
AN - SCOPUS:84883484949
SN - 1078-0432
VL - 19
SP - 4547
EP - 4549
JO - Clinical Cancer Research
JF - Clinical Cancer Research
IS - 17
ER -