Activity-based fluorescent reporters for monoamine oxidases in living cells

Aaron E. Albers; Katherine A. Rawls; Christopher J. Chang

doi:10.1039/b713190a

Activity-based fluorescent reporters for monoamine oxidases in living cells

Aaron E. Albers, Katherine A. Rawls, Christopher J. Chang

Research output: Contribution to journal › Article › peer-review

73 Scopus citations

Abstract

Monoamine Oxidase Reporters 1 and 2 (MR1 and MR2) are substrate-tethered activity probes that utilize a tandem amine oxidation/β-elimination mechanism to detect MAO chemistry in vitro and in living cells directly and specifically without the need for additional enzymes or other activating reagents.

Original language	English (US)
Pages (from-to)	4647-4649
Number of pages	3
Journal	Chemical Communications
Issue number	44
DOIs	https://doi.org/10.1039/b713190a
State	Published - 2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b713190a

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title = "Activity-based fluorescent reporters for monoamine oxidases in living cells",

abstract = "Monoamine Oxidase Reporters 1 and 2 (MR1 and MR2) are substrate-tethered activity probes that utilize a tandem amine oxidation/β-elimination mechanism to detect MAO chemistry in vitro and in living cells directly and specifically without the need for additional enzymes or other activating reagents.",

author = "Albers, {Aaron E.} and Rawls, {Katherine A.} and Chang, {Christopher J.}",

year = "2007",

doi = "10.1039/b713190a",

language = "English (US)",

pages = "4647--4649",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - Activity-based fluorescent reporters for monoamine oxidases in living cells

AU - Albers, Aaron E.

AU - Rawls, Katherine A.

AU - Chang, Christopher J.

PY - 2007

Y1 - 2007

N2 - Monoamine Oxidase Reporters 1 and 2 (MR1 and MR2) are substrate-tethered activity probes that utilize a tandem amine oxidation/β-elimination mechanism to detect MAO chemistry in vitro and in living cells directly and specifically without the need for additional enzymes or other activating reagents.

AB - Monoamine Oxidase Reporters 1 and 2 (MR1 and MR2) are substrate-tethered activity probes that utilize a tandem amine oxidation/β-elimination mechanism to detect MAO chemistry in vitro and in living cells directly and specifically without the need for additional enzymes or other activating reagents.

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U2 - 10.1039/b713190a

DO - 10.1039/b713190a

M3 - Article

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AN - SCOPUS:35949000072

SN - 1359-7345

SP - 4647

EP - 4649

JO - Chemical Communications

JF - Chemical Communications

IS - 44

ER -

Activity-based fluorescent reporters for monoamine oxidases in living cells

Abstract

All Science Journal Classification (ASJC) codes

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