@article{bae189b198664d5a90fbd89c085b379c,
title = "Actin and Rho GTPases in herpesvirus biology",
abstract = "Viruses have evolved a variety of interactions with host cells to create an optimal niche for viral replication, persistence and spread. The actin cytoskeleton of the host cell and actin-regulating Rho GTPase signaling pathways can be involved in several of these interactions. This review focuses on recent findings on herpesvirus interactions with actin and Rho GTPases during viral entry, replication in the nucleus and egress. Unraveling these often fascinating interactions might also provide additional insights into sometimes poorly known aspects of actin biology (e.g. its role in the nucleus) and in the development of novel antiviral therapies.",
author = "Favoreel, {Herman W.} and Enquist, {L. W.} and Becket Feierbach",
note = "Funding Information: We thank Silvia Piccinotti for the drawings used in this review. L.E. and B.F. are supported by the National Institute of Neurological Disorders and Stroke (NIH-NINDS; grant R01 33506) and the Dana Research Foundation. H.F. is supported by research grants from the Research Foundation – Flanders (F.W.O. Vlaanderen, grant nr. G.0196.06) and a Concerted Research Action fund of Ghent University. We thank all the present and past members of the Favoreel research group and the members of the Enquist laboratory. In particular, we would like to mention all the hard work of Geert Van Minnebruggen, Nick De Regge, C{\'e}line Van den Broeke, Matthias Deruelle, Sarah Glorieux and Silvia Piccinotti related to this topic. We also thank Hans Nauwynck for many fruitful discussions. We apologize to any colleagues whose work we were unable to mention because of space constraints.",
year = "2007",
month = sep,
doi = "10.1016/j.tim.2007.08.003",
language = "English (US)",
volume = "15",
pages = "426--433",
journal = "Trends in Microbiology",
issn = "0966-842X",
publisher = "Elsevier Ltd",
number = "9",
}