A stereoselective synthesis of a 2-functionalized-methyl-1β-methylcarbapenem key intermediate via decarboxylation

Woo Baeg Choi, Jaemoon Lee, Joseph E. Lynch, R. P. Volante, Paul J. Reider, Robert A. Reamer

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

An efficient synthesis of a key intermediate 2a for the synthesis of 2-functionalized methyl-1β-methylcarbapenem antibiotics 1 has been realized via a stereoselective decarboxylation reaction.

Original languageEnglish (US)
Pages (from-to)1817-1818
Number of pages2
JournalChemical Communications
Issue number17
DOIs
StatePublished - Sep 7 1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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