A soluble base for the copper-catalyzed imidazole N-arylations with aryl halides

Longbin Liu; Mike Frohn; Ning Xi; Celia Dominguez; Randy Hungate; Paul J. Reider

doi:10.1021/jo051640t

A soluble base for the copper-catalyzed imidazole N-arylations with aryl halides

Longbin Liu, Mike Frohn, Ning Xi, Celia Dominguez, Randy Hungate, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

184 Scopus citations

Abstract

CuI-catalyzed N-arylation of imidazoles with aryl bromides has been achieved in a near-homogeneous system that utilizes tetraethylammonium carbonate as base, 8-hydroxyquinoline as ligand, and H₂O as cosolvent. Preliminary results with aryl chlorides are also reported.

Original language	English (US)
Pages (from-to)	10135-10138
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	70
Issue number	24
DOIs	https://doi.org/10.1021/jo051640t
State	Published - Nov 25 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1021/jo051640t

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title = "A soluble base for the copper-catalyzed imidazole N-arylations with aryl halides",

abstract = "CuI-catalyzed N-arylation of imidazoles with aryl bromides has been achieved in a near-homogeneous system that utilizes tetraethylammonium carbonate as base, 8-hydroxyquinoline as ligand, and H2O as cosolvent. Preliminary results with aryl chlorides are also reported.",

author = "Longbin Liu and Mike Frohn and Ning Xi and Celia Dominguez and Randy Hungate and Reider, {Paul J.}",

year = "2005",

month = nov,

day = "25",

doi = "10.1021/jo051640t",

language = "English (US)",

volume = "70",

pages = "10135--10138",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "24",

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T1 - A soluble base for the copper-catalyzed imidazole N-arylations with aryl halides

AU - Liu, Longbin

AU - Frohn, Mike

AU - Xi, Ning

AU - Dominguez, Celia

AU - Hungate, Randy

AU - Reider, Paul J.

PY - 2005/11/25

Y1 - 2005/11/25

N2 - CuI-catalyzed N-arylation of imidazoles with aryl bromides has been achieved in a near-homogeneous system that utilizes tetraethylammonium carbonate as base, 8-hydroxyquinoline as ligand, and H2O as cosolvent. Preliminary results with aryl chlorides are also reported.

AB - CuI-catalyzed N-arylation of imidazoles with aryl bromides has been achieved in a near-homogeneous system that utilizes tetraethylammonium carbonate as base, 8-hydroxyquinoline as ligand, and H2O as cosolvent. Preliminary results with aryl chlorides are also reported.

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U2 - 10.1021/jo051640t

DO - 10.1021/jo051640t

M3 - Article

C2 - 16292856

AN - SCOPUS:28044443893

SN - 0022-3263

VL - 70

SP - 10135

EP - 10138

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 24

ER -

A soluble base for the copper-catalyzed imidazole N-arylations with aryl halides

Abstract

All Science Journal Classification (ASJC) codes

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