Abstract
Synthesis of the furopyridine 2 was accomplished in 52% overall yield from 6-hydroxynicotinic acid (3). The synthesis is highighted by a Heck coupling of 5 with ethylene followed by an NCS mediated oxidative cyclization and elimination sequence.
Original language | English (US) |
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Pages (from-to) | 4571-4574 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 36 |
Issue number | 26 |
DOIs | |
State | Published - Jun 26 1995 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry