Abstract
Understanding the regulation of β-catenin, a key component of the Wnt signalling pathway, has important implications for developmental processes, maintenance of stem cells and the formation of many cancers. The latest report suggests that a nuclear complex consisting of Pygopus and Legless is required for β-catenin's nuclear localization, thereby promoting its transcriptional activity.
Original language | English (US) |
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Pages (from-to) | 579-580 |
Number of pages | 2 |
Journal | Nature cell biology |
Volume | 6 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2004 |
All Science Journal Classification (ASJC) codes
- Cell Biology