A nuclear escort for β-catenin

Nicholas S. Tolwinski, Eric Wieschaus

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Understanding the regulation of β-catenin, a key component of the Wnt signalling pathway, has important implications for developmental processes, maintenance of stem cells and the formation of many cancers. The latest report suggests that a nuclear complex consisting of Pygopus and Legless is required for β-catenin's nuclear localization, thereby promoting its transcriptional activity.

Original languageEnglish (US)
Pages (from-to)579-580
Number of pages2
JournalNature Cell Biology
Volume6
Issue number7
DOIs
StatePublished - Jul 1 2004

All Science Journal Classification (ASJC) codes

  • Cell Biology

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