Abstract
TGF-β signaling promotes metastasis by controlling the expression of downstream target genes. In this issue of Cancer Cell, Yuan and colleagues discover a novel TGF-β-induced lncRNA, lncRNA-ATB, which stimulates EMT through sequestering miR-200s and facilitates colonization by stabilizing IL-11 mRNA, thus promoting both early and late steps of cancer metastasis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 557-559 |
| Number of pages | 3 |
| Journal | Cancer Cell |
| Volume | 25 |
| Issue number | 5 |
| DOIs | |
| State | Published - May 12 2014 |
All Science Journal Classification (ASJC) codes
- Oncology
- Cell Biology
- Cancer Research
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