A New Lnc in metastasis: Long noncoding RNA mediates the prometastatic functions of TGF-β

Wenyang Li; Yibin Kang

doi:10.1016/j.ccr.2014.04.014

A New Lnc in metastasis: Long noncoding RNA mediates the prometastatic functions of TGF-β

Wenyang Li, Yibin Kang

Research output: Contribution to journal › Short survey › peer-review

78 Scopus citations

Abstract

TGF-β signaling promotes metastasis by controlling the expression of downstream target genes. In this issue of Cancer Cell, Yuan and colleagues discover a novel TGF-β-induced lncRNA, lncRNA-ATB, which stimulates EMT through sequestering miR-200s and facilitates colonization by stabilizing IL-11 mRNA, thus promoting both early and late steps of cancer metastasis.

Original language	English (US)
Pages (from-to)	557-559
Number of pages	3
Journal	Cancer Cell
Volume	25
Issue number	5
DOIs	https://doi.org/10.1016/j.ccr.2014.04.014
State	Published - May 12 2014

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research
Cell Biology

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10.1016/j.ccr.2014.04.014

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title = "A New Lnc in metastasis: Long noncoding RNA mediates the prometastatic functions of TGF-β",

abstract = "TGF-β signaling promotes metastasis by controlling the expression of downstream target genes. In this issue of Cancer Cell, Yuan and colleagues discover a novel TGF-β-induced lncRNA, lncRNA-ATB, which stimulates EMT through sequestering miR-200s and facilitates colonization by stabilizing IL-11 mRNA, thus promoting both early and late steps of cancer metastasis.",

author = "Wenyang Li and Yibin Kang",

year = "2014",

month = may,

day = "12",

doi = "10.1016/j.ccr.2014.04.014",

language = "English (US)",

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pages = "557--559",

journal = "Cancer Cell",

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number = "5",

}

TY - JOUR

T1 - A New Lnc in metastasis

T2 - Long noncoding RNA mediates the prometastatic functions of TGF-β

AU - Li, Wenyang

AU - Kang, Yibin

PY - 2014/5/12

Y1 - 2014/5/12

N2 - TGF-β signaling promotes metastasis by controlling the expression of downstream target genes. In this issue of Cancer Cell, Yuan and colleagues discover a novel TGF-β-induced lncRNA, lncRNA-ATB, which stimulates EMT through sequestering miR-200s and facilitates colonization by stabilizing IL-11 mRNA, thus promoting both early and late steps of cancer metastasis.

AB - TGF-β signaling promotes metastasis by controlling the expression of downstream target genes. In this issue of Cancer Cell, Yuan and colleagues discover a novel TGF-β-induced lncRNA, lncRNA-ATB, which stimulates EMT through sequestering miR-200s and facilitates colonization by stabilizing IL-11 mRNA, thus promoting both early and late steps of cancer metastasis.

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U2 - 10.1016/j.ccr.2014.04.014

DO - 10.1016/j.ccr.2014.04.014

M3 - Short survey

C2 - 24823634

AN - SCOPUS:84900334614

SN - 1535-6108

VL - 25

SP - 557

EP - 559

JO - Cancer Cell

JF - Cancer Cell

IS - 5

ER -

A New Lnc in metastasis: Long noncoding RNA mediates the prometastatic functions of TGF-β

Abstract

All Science Journal Classification (ASJC) codes

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