A New Lnc in metastasis: Long noncoding RNA mediates the prometastatic functions of TGF-β

Wenyang Li, Yibin Kang

Research output: Contribution to journalShort survey

59 Scopus citations

Abstract

TGF-β signaling promotes metastasis by controlling the expression of downstream target genes. In this issue of Cancer Cell, Yuan and colleagues discover a novel TGF-β-induced lncRNA, lncRNA-ATB, which stimulates EMT through sequestering miR-200s and facilitates colonization by stabilizing IL-11 mRNA, thus promoting both early and late steps of cancer metastasis.

Original languageEnglish (US)
Pages (from-to)557-559
Number of pages3
JournalCancer Cell
Volume25
Issue number5
DOIs
StatePublished - May 12 2014

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cell Biology
  • Cancer Research

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