A multifaceted gradient in human cerebellum of structural and functional development

Xingyu Liu, Federico d’Oleire Uquillas, Angela N. Viaene, Zonglei Zhen, Jesse Gomez

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The organization of the basic tissue and functional properties of the cerebellum across development is unknown. Combining several large datasets, we demonstrate in the human cerebellum a static tissue gradient in adults that mirrors a similar growth-rate gradient across development. Quantitative tissue metrics corroborate unique densities of certain lipids and proteins among lobules, and cerebellar structural development closely follows cerebellar functional properties through childhood.

Original languageEnglish (US)
Pages (from-to)1129-1133
Number of pages5
JournalNature neuroscience
Volume25
Issue number9
DOIs
StatePublished - Sep 2022

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

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