Abstract
The synthesis and catalytic activity of [(TMEDA)Ni(o-tolyl)Cl], an air-stable, crystalline solid, is described. This complex is an effective precatalyst in a variety of nickel-catalyzed transformations. The lability of TMEDA allows a wide variety of ligands to be used, including mono- and bidentate phosphines, diimines, and N-heterocyclic carbenes. Preliminary mechanistic studies are also reported, which suggest that [(TMEDA)Ni(o-tolyl)Cl] can activate by either a Ni-B or Ni-Ni transmetalation event, depending on the reaction conditions.
Original language | English (US) |
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Pages (from-to) | 2166-2169 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 17 |
Issue number | 9 |
DOIs | |
State | Published - May 1 2015 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry