A metabolic strategy to reverse fibrosis?

Joshua D. Rabinowitz, Gökhan M. Mutlu

Research output: Contribution to journalComment/debate

1 Scopus citations

Abstract

Fibrosis is characterized by excessive extracellular matrix (ECM) production relative to catabolism. A new study shows that the fuel choice of fibroblasts impacts this balance, with glycolysis promoting ECM synthesis and fatty acid oxidation stimulating ECM degradation.

Original languageEnglish (US)
Pages (from-to)12-13
Number of pages2
JournalNature Metabolism
Volume1
Issue number1
DOIs
StatePublished - Jan 1 2019

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Physiology (medical)
  • Internal Medicine
  • Cell Biology

Fingerprint Dive into the research topics of 'A metabolic strategy to reverse fibrosis?'. Together they form a unique fingerprint.

  • Cite this