A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision

Justin E. Silpe; Bonnie Lynn Bassler

doi:10.1016/j.cell.2018.10.059

A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision

Justin E. Silpe, Bonnie Lynn Bassler

Research output: Contribution to journal › Article › peer-review

218 Scopus citations

Abstract

Bacteriophages can “listen in” on their host bacterium's quorum-sensing systems, shifting their lysis-lysogeny decisions based on host cell density.

Original language	English (US)
Pages (from-to)	268-280.e13
Journal	Cell
Volume	176
Issue number	1-2
DOIs	https://doi.org/10.1016/j.cell.2018.10.059
State	Published - Jan 10 2019

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

Keywords

DPO
Qtip
Vibrio
VqmA
antirepressor
autoinducer
kill switch
lysis-lysogeny
phage
quorum sensing

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10.1016/j.cell.2018.10.059

Cite this

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title = "A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision",

abstract = "Bacteriophages can “listen in” on their host bacterium's quorum-sensing systems, shifting their lysis-lysogeny decisions based on host cell density.",

keywords = "DPO, Qtip, Vibrio, VqmA, antirepressor, autoinducer, kill switch, lysis-lysogeny, phage, quorum sensing",

author = "Silpe, {Justin E.} and Bassler, {Bonnie Lynn}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2019",

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T1 - A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision

AU - Silpe, Justin E.

AU - Bassler, Bonnie Lynn

PY - 2019/1/10

Y1 - 2019/1/10

N2 - Bacteriophages can “listen in” on their host bacterium's quorum-sensing systems, shifting their lysis-lysogeny decisions based on host cell density.

AB - Bacteriophages can “listen in” on their host bacterium's quorum-sensing systems, shifting their lysis-lysogeny decisions based on host cell density.

KW - DPO

KW - Qtip

KW - Vibrio

KW - VqmA

KW - antirepressor

KW - autoinducer

KW - kill switch

KW - lysis-lysogeny

KW - phage

KW - quorum sensing

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AN - SCOPUS:85059602498

SN - 0092-8674

VL - 176

SP - 268-280.e13

JO - Cell

JF - Cell

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ER -

A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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