A highly efficient synthesis of fibrinogen receptor antagonist L-734,217 via a novel chemoselective silyl-mediated conjugate addition of δ-lactams to 4-vinylpyridine

  • John Y.L. Chung
  • , David L. Hughes
  • , Dalian Zhao
  • , Zhiguo Song
  • , David J. Mathre
  • , Guo Jie Ho
  • , James M. McNamara
  • , Alan W. Douglas
  • , R. A. Reamer
  • , Fuh Rong Tsay
  • , Richard Varsolona
  • , James McCauley
  • , Edward J.J. Grabowski
  • , Paul J. Reider

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Chemistry