A general strategy for organocatalytic activation of c-h bonds via photoredox catalysis: Direct arylation of benzylic ethers

Katrine Qvortrup, Danica A. Rankic, David W.C. MacMillan

Research output: Contribution to journalArticle

155 Scopus citations

Abstract

Direct C-H functionalization and arylation of benzyl ethers has been accomplished via photoredox organocatalysis. The productive merger of a thiol catalyst and a commercially available iridium photoredox catalyst in the presence of household light directly affords benzylic arylation products in good to excellent yield. The utility of this methodology is further demonstrated in direct arylation of 2,5-dihydrofuran to form a single regioisomer.

Original languageEnglish (US)
Pages (from-to)626-629
Number of pages4
JournalJournal of the American Chemical Society
Volume136
Issue number2
DOIs
StatePublished - Jan 15 2014

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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