@article{3440874c93f0455c99ed791932a33fce,
title = "A General Small-Scale Reactor to Enable Standardization and Acceleration of Photocatalytic Reactions",
abstract = "Photocatalysis for organic synthesis has experienced an exponential growth in the past 10 years. However, the variety of experimental procedures that have been reported to perform photon-based catalyst excitation has hampered the establishment of general protocols to convert visible light into chemical energy. To address this issue, we have designed an integrated photoreactor for enhanced photon capture and catalyst excitation. Moreover, the evaluation of this new reactor in eight photocatalytic transformations that are widely employed in medicinal chemistry settings has confirmed significant performance advantages of this optimized design while enabling a standardized protocol.",
author = "Le, {Chi Chip} and Wismer, {Michael K.} and Shi, {Zhi Cai} and Rui Zhang and Conway, {Donald V.} and Guoqing Li and Petr Vachal and Davies, {Ian W.} and MacMillan, {David W.C.}",
note = "Funding Information: Financial support was provided by the NIH NIGMS (R01 GM103558-06) and kind gifts from Merck, Bristol-Myers Squibb, Abbvie, Janssen and Eli Lilly. We would like to thank the following scientists and engineers at Merck & Co., Inc., and Princeton University for input on reactor design and experimental and technical assistance during preproduction validation of the units. From Princeton University: Patricia Zhang, Megan Shaw, Ryan Evans, Russell Smith, Jack Twilton and Jack Terrett. From Merck & Co., Inc. Publisher Copyright: {\textcopyright} 2017 American Chemical Society.",
year = "2017",
month = jun,
day = "28",
doi = "10.1021/acscentsci.7b00159",
language = "English (US)",
volume = "3",
pages = "647--653",
journal = "ACS Central Science",
issn = "2374-7943",
publisher = "American Chemical Society",
number = "6",
}