A General Small-Scale Reactor to Enable Standardization and Acceleration of Photocatalytic Reactions

Chi Chip Le, Michael K. Wismer, Zhi Cai Shi, Rui Zhang, Donald V. Conway, Guoqing Li, Petr Vachal, Ian W. Davies, David W.C. MacMillan

Research output: Contribution to journalArticle

74 Scopus citations

Abstract

Photocatalysis for organic synthesis has experienced an exponential growth in the past 10 years. However, the variety of experimental procedures that have been reported to perform photon-based catalyst excitation has hampered the establishment of general protocols to convert visible light into chemical energy. To address this issue, we have designed an integrated photoreactor for enhanced photon capture and catalyst excitation. Moreover, the evaluation of this new reactor in eight photocatalytic transformations that are widely employed in medicinal chemistry settings has confirmed significant performance advantages of this optimized design while enabling a standardized protocol.

Original languageEnglish (US)
Pages (from-to)647-653
Number of pages7
JournalACS Central Science
Volume3
Issue number6
DOIs
StatePublished - Jun 28 2017

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Fingerprint Dive into the research topics of 'A General Small-Scale Reactor to Enable Standardization and Acceleration of Photocatalytic Reactions'. Together they form a unique fingerprint.

  • Cite this

    Le, C. C., Wismer, M. K., Shi, Z. C., Zhang, R., Conway, D. V., Li, G., Vachal, P., Davies, I. W., & MacMillan, D. W. C. (2017). A General Small-Scale Reactor to Enable Standardization and Acceleration of Photocatalytic Reactions. ACS Central Science, 3(6), 647-653. https://doi.org/10.1021/acscentsci.7b00159