A flexible EEG acquisition and biomarker extraction system based on thin-film electronics

Tiffany Moy, Liechao Huang, Warren Rieutort-Louis, Sigurd Wagner, James C. Sturm, Naveen Verma

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

Abstract

EEG is an important modality for many medical purposes. However, the low-amplitude of signals (10-to-100μV) and large number of channels (∼20) raise numerous challenges, including electrode setup (correct placement, skin preparation, sanitation), patient comfort (number of channels, skin abrasion), and robust acquisition (electrode/wire motion artifacts, wire stray coupling). The recent emergence of low-cost, single-use, flexible, pre-gelled electrode arrays, as in Fig. 16.4.1, delivers significant advantages [1]. Today, these are passive, requiring connection to external readout electronics via a many-channel cable. We present the system in Fig. 16.4.1, having similar flexible form factor, but with the following enhancements: (1) embedded low-noise chopper-stabilized amplifiers using amorphous-silicon (a-Si) thin-film transistors (TFTs) compatible with flexible substrates (i.e. low-temperature-processed, 20 EEG channels onto a single interface using TFT scanning circuits, to substantially ease connection with an embedded IC; and (3) an algorithm whereby spectral-energy features, a generic EEG biomarker, are derived directly from the compressed signals (by a conventional CMOS IC). Seizure detection from the extracted features is demonstrated via analog replay of patient EEG through the system.

Original languageEnglish (US)
Title of host publication2016 IEEE International Solid-State Circuits Conference, ISSCC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages294-295
Number of pages2
ISBN (Electronic)9781467394666
DOIs
StatePublished - Feb 23 2016
Event63rd IEEE International Solid-State Circuits Conference, ISSCC 2016 - San Francisco, United States
Duration: Jan 31 2016Feb 4 2016

Publication series

NameDigest of Technical Papers - IEEE International Solid-State Circuits Conference
Volume59
ISSN (Print)0193-6530

Other

Other63rd IEEE International Solid-State Circuits Conference, ISSCC 2016
CountryUnited States
CitySan Francisco
Period1/31/162/4/16

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

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