@article{8d046eefd4fd4bac95d38a4edba881a1,
title = "A fiber optic-nanophotonic approach to the detection of antibodies and viral particles of COVID-19",
abstract = "Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on {"}Meet the Press{"}that {"}[T]he U.S. needs a 'breakthrough' in coronavirus testing to help screen Americans and get a more accurate picture of the virus' spread.{"}We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest of both physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVID-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper.",
keywords = "detection of SAR-CoV-2 virus, hollow-core fibers, laser spectroscopic technique, nanophotonics",
author = "Navid Rajil and Alexei Sokolov and Zhenhuan Yi and Garry Adams and Girish Agarwal and Vsevolod Belousov and Robert Brick and Kimberly Chapin and Jeffrey Cirillo and Volker Deckert and Sahar Delfan and Shahriar Esmaeili and Alma Fern{\'a}ndez-Gonz{\'a}lez and Edward Fry and Zehua Han and Philip Hemmer and George Kattawar and Moochan Kim and Lee, {Ming Che} and Lu, {Chao Yang} and Jon Mogford and Benjamin Neuman and Pan, {Jian Wei} and Tao Peng and Vincent Poor and Steven Scully and Yanhua Shih and Szymon Suckewer and Anatoly Svidzinsky and Aart Verhoef and Dawei Wang and Kai Wang and Lan Yang and Aleksei Zheltikov and Shiyao Zhu and Suhail Zubairy and Marlan Scully",
note = "Funding Information: The research was supported by the Robert A. Welch Foundation (Grant No. A-1943, A-1547, and A-1261), the Air Force Office of Scientific Research (Award No. FA9550-20-1-0366 DEF), National Science Foundation (Grant No. PHY-2013771), Office of Naval Research (Grant No. N00014-20-1-2184), Texas A&M Foundation, National Institutes of Health (Grant No. AI104960), and the Government of the Russian Federation (14.W03.31.0028). This research is also supported by King Abdulaziz City for Science and Technology (KACST). Funding Information: Research funding: The research was supported by the Robert A. Welch Foundation (Grant No. A-1943, A-1547, and A-1261), the Air Force Office of Scientific Research (Award No. FA9550-20-1-0366 DEF), National Science Foundation (Grant No. PHY-2013771), Office of Naval Research (Grant No. N00014-20-1-2184), Texas A&M Foundation, National Institutes of Health (Grant No. AI104960), and the Government of the Russian Federation (14.W03.31.0028). This research is also supported by King Abdulaziz City for Science and Technology (KACST). Funding Information: M. O. S. thanks Chancellor John Sharp for many stimulating discussions and he thanks the Robert A. Welch Foundation, the Air Force Office of Scientific Research, the National Science Foundation (NSF), the Office of Naval Research, and King Abdulaziz City for Science and Technology (KACST) for support. The authors thank Jane Pryor, and Maria Bermudez Cruz for helpful discussions. N. R., S. D., C. L., S. E., M. L. are supported by the Herman F. Heep and Minnie Belle Heep Texas A&M University Endowed Fund held/administered by the Texas A&M Foundation. J. D. C. is supported in part from funds provided by the Texas A&M University System and National Institutes of Health Grant AI104960. P. H. acknowledges financial support from the Government of the Russian Federation (Mega-grant No. 14.W03.31.0028). G. S. A. thanks the Robert A. Welch Foundation grant no A-1943 and the AFOSR award No. FA9550-18-1-0141 for support. A. S. acknowledges the support from the Robert A. Welch Foundation grant no A-1547. A. Z. acknowledges support from the Welch Foundation (Grant No. A-1801-20180324). V. B. and A. Z. acknowledge support from the Russian Foundation for Basic Research (project Nos. 17-00-00212 and 17-00-00214). V. D. acknowledges support from German Research Foundation (CRC 1375 - NOA - C2). V.P. acknowledges the support of the U.S. Army Research Office under Grant W911NF-20-1-0204, the U.S. National Science Foundation under RAPID Grant IIS-2026982, and a grant from the C3.ai Digital Transformation Institute. Publisher Copyright: {\textcopyright} 2020 Navid Rajil et al., published by De Gruyter, Berlin/Boston 2020.",
year = "2020",
doi = "10.1515/nanoph-2020-0357",
language = "English (US)",
volume = "10",
pages = "235--246",
journal = "Nanophotonics",
issn = "2192-8606",
publisher = "Walter De Gruyter",
number = "1",
}