Abstract
Investigation into the selectivity observed in the synthesis of 1β-methylcarbapenems was carried out by examining (1) the rotational barrier between the two possible ketene acetal conformations A and B and (2) the protonation of ketene acetal 3 to the mono acid product 2, using the MNDO Hamiltonian.
Original language | English (US) |
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Pages (from-to) | 3749-3751 |
Number of pages | 3 |
Journal | Journal of Organic Chemistry |
Volume | 59 |
Issue number | 14 |
DOIs | |
State | Published - Jul 1 1994 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Organic Chemistry