A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes

W. McGinnis, M. S. Levine, E. Hafen, A. Kuroiwa, W. J. Gehring

Research output: Contribution to journalArticlepeer-review

792 Scopus citations

Abstract

A repetitive DNA sequence has been identified in the Drosophila melanogaster genome that appears to be localized specifically within genes of the bithorax and Antennapedia complexes that are required for correct segmental development. Initially identified in cloned copies of the genes Antennapedia, Ultrabithorax and fushi tarazu, the sequence is also contained within two other DNA clones that have characteristics strongly suggesting that they derive from other homoeotic genes.

Original languageEnglish (US)
Pages (from-to)428-433
Number of pages6
JournalNature
Volume308
Issue number5958
DOIs
StatePublished - 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General

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