A concise and convergent synthesis of PA-824

Maurice A. Marsini, Paul J. Reider, Erik J. Sorensen

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

An efficient four-step synthesis of PA-824, a promising antituberculosis drug candidate, has been developed. This concise approach offers significant improvements over the synthetic route currently used for large-scale production.

Original languageEnglish (US)
Pages (from-to)7479-7482
Number of pages4
JournalJournal of Organic Chemistry
Volume75
Issue number21
DOIs
StatePublished - Nov 5 2010

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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