A chemical synthesis of 11-methoxy mitragynine pseudoindoxyl featuring the interrupted Ugi reaction

Keyphrases

• Ugi Reaction 100%
• Mitragynine 100%
• A. Chemical Synthesis 100%
• Opioid Agonist 33%
• Aromatic Ring 33%
• Electrophilic 33%
• Functionalized piperidines 33%
• Lactones 33%
• Staged Construction 33%
• Reductive Cyclization 33%
• Internal Attacks 33%
• Ring Annulation 33%
• Electron-rich Aromatics 33%
• Indoxyl 33%
• Nitrilium Ion 33%
• Attractive Alternatives 33%
• Piperidine Ring 33%

Chemistry

• Mitragynine 100%
• Ugi Condensation 100%
• Piperidine 33%
• Indoxyl 33%
• Ring Formation 33%
• Aromatic Structure 33%
• Reductive Cyclization 33%
• Lactone 33%

Medicine and Dentistry

• Mitragynine 100%
• Lactone 33%
• Piperidine 33%
• Opiate Agonist 33%
• Indole Derivative 33%