2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate

Hao Tang; Suresh Venkatesh; Zhongtian Lin; Xuyang Lu; Hooman Saeidi; Gulam M. Rather; Joseph R. Bertino; Chen Yong Lin; Mehdi Javanmard; Kaushik Sengupta

doi:10.1109/CICC.2019.8780363

2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate

Hao Tang, Suresh Venkatesh, Zhongtian Lin, Xuyang Lu, Hooman Saeidi, Gulam M. Rather, Joseph R. Bertino, Chen Yong Lin, Mehdi Javanmard, Kaushik Sengupta

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

8 Scopus citations

Abstract

In this article, we present a 2D oscillator array-based magnetic sensor CMOS IC for flow cytometry. The CMOS IC packaged with a microfluidic channel eliminates the need for hydro-focusing by allowing uninhibited flow over the 2D chip surface. The chip exploits multi-site detection capability allowing simultaneously high flow rate for trace cell detection, reduced false positives, and real-time cell tracking. We demonstrate these functionalities with a 7 × 7 array in 65-nm CMOS with lymphoma cancer cells.

Original language	English (US)
Title of host publication	2019 IEEE Custom Integrated Circuits Conference, CICC 2019
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781538693957
DOIs	https://doi.org/10.1109/CICC.2019.8780363
State	Published - Apr 2019
Externally published	Yes
Event	40th Annual IEEE Custom Integrated Circuits Conference, CICC 2019 - Austin, United States Duration: Apr 14 2019 → Apr 17 2019

Publication series

Name	Proceedings of the Custom Integrated Circuits Conference
Volume	2019-April
ISSN (Print)	0886-5930

Conference

Conference	40th Annual IEEE Custom Integrated Circuits Conference, CICC 2019
Country/Territory	United States
City	Austin
Period	4/14/19 → 4/17/19

All Science Journal Classification (ASJC) codes

Electrical and Electronic Engineering

Access to Document

10.1109/CICC.2019.8780363

Cite this

Tang, H., Venkatesh, S., Lin, Z., Lu, X., Saeidi, H., Rather, G. M., Bertino, J. R., Lin, C. Y., Javanmard, M., & Sengupta, K. (2019). 2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate. In 2019 IEEE Custom Integrated Circuits Conference, CICC 2019 Article 8780363 (Proceedings of the Custom Integrated Circuits Conference; Vol. 2019-April). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CICC.2019.8780363

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title = "2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate",

abstract = "In this article, we present a 2D oscillator array-based magnetic sensor CMOS IC for flow cytometry. The CMOS IC packaged with a microfluidic channel eliminates the need for hydro-focusing by allowing uninhibited flow over the 2D chip surface. The chip exploits multi-site detection capability allowing simultaneously high flow rate for trace cell detection, reduced false positives, and real-time cell tracking. We demonstrate these functionalities with a 7 × 7 array in 65-nm CMOS with lymphoma cancer cells.",

author = "Hao Tang and Suresh Venkatesh and Zhongtian Lin and Xuyang Lu and Hooman Saeidi and Rather, {Gulam M.} and Bertino, {Joseph R.} and Lin, {Chen Yong} and Mehdi Javanmard and Kaushik Sengupta",

note = "Publisher Copyright: {\textcopyright} 2019 IEEE.; 40th Annual IEEE Custom Integrated Circuits Conference, CICC 2019 ; Conference date: 14-04-2019 Through 17-04-2019",

year = "2019",

month = apr,

doi = "10.1109/CICC.2019.8780363",

language = "English (US)",

series = "Proceedings of the Custom Integrated Circuits Conference",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

booktitle = "2019 IEEE Custom Integrated Circuits Conference, CICC 2019",

address = "United States",

}

Tang, H, Venkatesh, S, Lin, Z, Lu, X, Saeidi, H, Rather, GM, Bertino, JR, Lin, CY, Javanmard, M & Sengupta, K 2019, 2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate. in 2019 IEEE Custom Integrated Circuits Conference, CICC 2019., 8780363, Proceedings of the Custom Integrated Circuits Conference, vol. 2019-April, Institute of Electrical and Electronics Engineers Inc., 40th Annual IEEE Custom Integrated Circuits Conference, CICC 2019, Austin, United States, 4/14/19. https://doi.org/10.1109/CICC.2019.8780363

2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate. / Tang, Hao; Venkatesh, Suresh; Lin, Zhongtian et al.
2019 IEEE Custom Integrated Circuits Conference, CICC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. 8780363 (Proceedings of the Custom Integrated Circuits Conference; Vol. 2019-April).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - 2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate

AU - Tang, Hao

AU - Venkatesh, Suresh

AU - Lin, Zhongtian

AU - Lu, Xuyang

AU - Saeidi, Hooman

AU - Rather, Gulam M.

AU - Bertino, Joseph R.

AU - Lin, Chen Yong

AU - Javanmard, Mehdi

AU - Sengupta, Kaushik

PY - 2019/4

Y1 - 2019/4

N2 - In this article, we present a 2D oscillator array-based magnetic sensor CMOS IC for flow cytometry. The CMOS IC packaged with a microfluidic channel eliminates the need for hydro-focusing by allowing uninhibited flow over the 2D chip surface. The chip exploits multi-site detection capability allowing simultaneously high flow rate for trace cell detection, reduced false positives, and real-time cell tracking. We demonstrate these functionalities with a 7 × 7 array in 65-nm CMOS with lymphoma cancer cells.

AB - In this article, we present a 2D oscillator array-based magnetic sensor CMOS IC for flow cytometry. The CMOS IC packaged with a microfluidic channel eliminates the need for hydro-focusing by allowing uninhibited flow over the 2D chip surface. The chip exploits multi-site detection capability allowing simultaneously high flow rate for trace cell detection, reduced false positives, and real-time cell tracking. We demonstrate these functionalities with a 7 × 7 array in 65-nm CMOS with lymphoma cancer cells.

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M3 - Conference contribution

AN - SCOPUS:85070557875

T3 - Proceedings of the Custom Integrated Circuits Conference

BT - 2019 IEEE Custom Integrated Circuits Conference, CICC 2019

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 40th Annual IEEE Custom Integrated Circuits Conference, CICC 2019

Y2 - 14 April 2019 through 17 April 2019

ER -

Tang H, Venkatesh S, Lin Z, Lu X, Saeidi H, Rather GM et al. 2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate. In 2019 IEEE Custom Integrated Circuits Conference, CICC 2019. Institute of Electrical and Electronics Engineers Inc. 2019. 8780363. (Proceedings of the Custom Integrated Circuits Conference). doi: 10.1109/CICC.2019.8780363

2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate

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