2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate

Hao Tang, Suresh Venkatesh, Zhongtian Lin, Xuyang Lu, Hooman Saeidi, Gulam M. Rather, Joseph R. Bertino, Chen Yong Lin, Mehdi Javanmard, Kaushik Sengupta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

In this article, we present a 2D oscillator array-based magnetic sensor CMOS IC for flow cytometry. The CMOS IC packaged with a microfluidic channel eliminates the need for hydro-focusing by allowing uninhibited flow over the 2D chip surface. The chip exploits multi-site detection capability allowing simultaneously high flow rate for trace cell detection, reduced false positives, and real-time cell tracking. We demonstrate these functionalities with a 7 × 7 array in 65-nm CMOS with lymphoma cancer cells.

Original languageEnglish (US)
Title of host publication2019 IEEE Custom Integrated Circuits Conference, CICC 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781538693957
DOIs
StatePublished - Apr 2019
Event40th Annual IEEE Custom Integrated Circuits Conference, CICC 2019 - Austin, United States
Duration: Apr 14 2019Apr 17 2019

Publication series

NameProceedings of the Custom Integrated Circuits Conference
Volume2019-April
ISSN (Print)0886-5930

Conference

Conference40th Annual IEEE Custom Integrated Circuits Conference, CICC 2019
Country/TerritoryUnited States
CityAustin
Period4/14/194/17/19

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

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