@inproceedings{cbe75d15241d4b1a85fdd7c1d8b05d0a,
title = "2 Min-incubation and 6 pM-sensitivity microfluidic fluorescence immunoassay - A novel method for further significant enhancement using local electrical field on nanoplasmonic signal amplification surface",
abstract = "Previously, we have demonstrated (a) a new nanoplasmonic surface (D2PA) [1] that enhances fluorescence assay (LoD) by 106 fold (to 300 aM) for 96-well-microtiter and 100 μL sample volume [2]; and (b) an microfluidic devices with D2PA inside microchannel that has a LoD enhancement of 104 fold (to 136 pM) for 120 nL sample volume and an incubation time reduction by 6 fold (to 20 mins)[3, 4]. Here we report a new method [5] that offers further significant enhancements over the previous enhancements, achieving additional 23-fold sensitivity increase (to 6 pM, 120 nL sample volume) and addtional 10 fold incubation time reduction (to 2 min), by creating local electrical field and gradient on D2PA.",
keywords = "Acceleration, D2PA, Electric field, Enhanced sensitivity, Immunoassay",
author = "Ruoming Peng and Liangcheng Zhou and Qi Zhang and Wei Ding and Chou, {Stephen Y.}",
note = "Publisher Copyright: {\textcopyright} 14CBMS.; 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",
year = "2014",
language = "English (US)",
series = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
publisher = "Chemical and Biological Microsystems Society",
pages = "1832--1834",
booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",
}