β-regioselective intermolecular Heck arylation of N,N-disubstituted allylamines

J. Wu; J. F. Marcoux; I. W. Davies; P. J. Reider

doi:10.1016/S0040-4039(00)01914-6

β-regioselective intermolecular Heck arylation of N,N-disubstituted allylamines

J. Wu
, J. F. Marcoux
, I. W. Davies
, P. J. Reider

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.

Original language	English (US)
Pages (from-to)	159-162
Number of pages	4
Journal	Tetrahedron Letters
Volume	42
Issue number	2
DOIs	https://doi.org/10.1016/S0040-4039(00)01914-6
State	Published - Jan 8 2001
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)01914-6

Cite this

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abstract = "β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.",

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T1 - β-regioselective intermolecular Heck arylation of N,N-disubstituted allylamines

AU - Wu, J.

AU - Marcoux, J. F.

AU - Davies, I. W.

AU - Reider, P. J.

PY - 2001/1/8

Y1 - 2001/1/8

N2 - β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.

AB - β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.

UR - https://www.scopus.com/pages/publications/0035825037

UR - https://www.scopus.com/pages/publications/0035825037#tab=citedBy

U2 - 10.1016/S0040-4039(00)01914-6

DO - 10.1016/S0040-4039(00)01914-6

M3 - Article

AN - SCOPUS:0035825037

SN - 0040-4039

VL - 42

SP - 159

EP - 162

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 2

ER -

β-regioselective intermolecular Heck arylation of N,N-disubstituted allylamines

Abstract

All Science Journal Classification (ASJC) codes

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