β-regioselective intermolecular Heck arylation of N,N-disubstituted allylamines

J. Wu, J. F. Marcoux, I. W. Davies, P. J. Reider

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.

Original languageEnglish (US)
Pages (from-to)159-162
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number2
DOIs
StatePublished - Jan 8 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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