β-regioselective intermolecular Heck arylation of N,N-disubstituted allylamines

J. Wu; J. F. Marcoux; I. W. Davies; P. J. Reider

doi:10.1016/S0040-4039(00)01914-6

β-regioselective intermolecular Heck arylation of N,N-disubstituted allylamines

J. Wu, J. F. Marcoux, I. W. Davies, P. J. Reider

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.

Original language	English (US)
Pages (from-to)	159-162
Number of pages	4
Journal	Tetrahedron Letters
Volume	42
Issue number	2
DOIs	https://doi.org/10.1016/S0040-4039(00)01914-6
State	Published - Jan 8 2001
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)01914-6

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abstract = "β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.",

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AU - Wu, J.

AU - Marcoux, J. F.

AU - Davies, I. W.

AU - Reider, P. J.

PY - 2001/1/8

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N2 - β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.

AB - β-Regioselectivity has been demonstrated for the Heck arylation of N,N-disubstituted allylamines. The scope and limitations of the reaction were demonstrated by the coupling of N,N-dibenzylallylamine with a variety of substituted aryl triflates. This methodology represents a straightforward approach for the efficient preparation of a variety of primary β-aryl allyl amines.

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JO - Tetrahedron Letters

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ER -

β-regioselective intermolecular Heck arylation of N,N-disubstituted allylamines

Abstract

All Science Journal Classification (ASJC) codes

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