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Dive into the research topics where Ralph Elliot Kleiner is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Chemical approaches to investigate post-transcriptional RNA regulation
Kleiner, R. E. (PI)
8/1/26 → 7/31/30
Project: Research project
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MFB: Dynamic cellular RNA imaging with metabolically incorporated fluorescent nucleosides
Kleiner, R. E. (PI)
NSF - National Science Foundation
9/1/25 → 8/31/28
Project: Research project
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PPM: Illuminating the Dihydrouridine Epitranscriptome
Kleiner, R. E. (PI)
NSF - National Science Foundation
2/15/25 → 1/31/28
Project: Research project
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An RNA editing platform to investigate the dynamic RNA interactome
Kleiner, R. E. (PI)
9/21/24 → 8/31/26
Project: Research project
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CAREER: A chemoproteomic strategy to decipher epitranscriptomic pyrimidine modifications
Kleiner, R. E. (PI)
NSF - National Science Foundation
12/15/19 → 11/30/24
Project: Research project
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Activity-based profiling of bacterial RNA-modifying enzymes reveals species-specific 5-methyluridine modification in Bacillus subtilis 23S rRNA
Jaber, Q. Z., Yu, N. J., Masuda, I., Hou, Y. M. & Kleiner, R. E., Sep 29 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 39, e2613881123.Research output: Contribution to journal › Article › peer-review
Open Access -
Metabolism of Epigenetic Ribonucleosides Leads to Nucleolar Stress and Cytotoxicity
Sun, X., Donlic, A., Boyer, J. A., Press, T. E., Kim, M., Reddy, N. K., Brangwynne, C. P., Rabinowitz, J. D. & Kleiner, R. E., Mar 20 2026, In: ACS chemical biology. 21, 3, p. 446-456 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Quantitative profiling of RNA modifications enriched in non-membrane-bound cellular structures using APEX-RNA-MS
Seo, K. W., Dhingani, D. Y. & Kleiner, R. E., Sep 17 2026, In: Cell Chemical Biology. 33, 9, p. 1310-1321.e5Research output: Contribution to journal › Article › peer-review
Open Access -
Structure of ergosteryl-aspartate synthase reveals how an entrapped tRNA is used like a prosthetic swinging arm in the synthesis of aminoacylated sterols
Murayama, H., Yakobov, N., Mahmoudi, N., Legrosdidier, S., Fournier, N., Zuttion, S., Matsumoto, K., Nishimura, M., Ji, J., Senger, B., Huck, L., Gamper, H. B., Kise, Y., Kleiner, R. E., Frechin, M., Hou, Y. M., Becker, H. D., Itoh, Y., Fischer, F. & Nureki, O., Dec 2026, In: Nature communications. 17, 1, 4455.Research output: Contribution to journal › Article › peer-review
Open Access -
Amino acid changes in two viral proteins drive attenuation of the yellow fever 17D vaccine
Zhang, J., Chavez, E. C., Winkler, M., Liu, J., Carver, S., Lin, A. E., Biswas, A., Tamura, T., Tseng, A., Wang, D., Benhamou, A., O’ Connell, A. K., Matsuo, M., Norton, J. E., Kenney, D., Adamson, B., Kleiner, R. E., Burwitz, B., Crossland, N. A. & Douam, F. & 1 others, , Aug 2025, In: Nature Microbiology. 10, 8, p. 1902-1917 16 p.Research output: Contribution to journal › Article › peer-review
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