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Dive into the research topics where Nieng Yan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Structural Investigation of the Gating and Regulatory Mechanism of Voltage-gated Ca2+ Channels
1/1/19 → 11/30/22
Project: Research project
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Structural and Functional Analysis of Cardiac Ryanodine Receptor Pharmacotherapy in Lipid Bilayer
9/1/19 → 8/31/20
Project: Research project
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Structural and Biochemical Investigation of Tumor Suppressor Patched1 in Hedgehog Pathway
NJ Commission on Cancer Research
1/1/19 → 12/31/20
Project: Research project
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A structure of human scap bound to insig-2 suggests how their interaction is regulated by sterols
Yan, R., Cao, P., Song, W., Qian, H., Du, X., Coates, H. W., Zhao, X., Li, Y., Gao, S., Gong, X., Liu, X., Sui, J., Lei, J., Yang, H., Brown, A. J., Zhou, Q., Yan, C. & Yan, N., Mar 5 2021, In: Science. 371, 6533, eabb2224.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies
Pan, X., Li, Z., Jin, X., Zhao, Y., Huang, G., Huang, X., Shen, Z., Cao, Y., Dong, M., Lei, J. & Yan, N., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 11, e2100066118.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Orthosteric–allosteric dual inhibitors of PfHT1 as selective antimalarial agents
Huang, J., Yuan, Y., Zhao, N., Pu, D., Tang, Q., Zhang, S., Luo, S., Yang, X., Wang, N., Xiao, Y., Zhang, T., Liu, Z., Sakata-Kato, T., Jiang, X., Kato, N., Yan, N. & Yin, H., Jan 19 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 3, e2017749118.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Nav1.5 by the Antiarrhythmic Drug Quinidine**
Li, Z., Jin, X., Wu, T., Huang, G., Wu, K., Lei, J., Pan, X. & Yan, N., May 10 2021, In: Angewandte Chemie - International Edition. 60, 20, p. 11474-11480 7 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Structural basis for sterol sensing by Scap and Insig
Yan, R., Cao, P., Song, W., Li, Y., Wang, T., Qian, H., Yan, C. & Yan, N., Jun 29 2021, In: Cell Reports. 35, 13, 109299.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations