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Dive into the research topics where Michael H. Hecht is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Life Sustaining Enzymes From Non-Natural Sequences
Hecht, M. H. (PI)
NSF - National Science Foundation
2/1/20 → 1/31/26
Project: Research project
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Computationally Designed Protein Libraries for the Selection of Novel Enzymes
Hecht, M. H. (PI)
8/1/14 → 7/31/15
Project: Research project
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Toward Artificial Proteomes
Hecht, M. H. (PI)
NSF - National Science Foundation
7/1/14 → 6/30/19
Project: Research project
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Design, Engineering, and Selection of Novel Proteins
Hecht, M. H. (PI)
NSF - National Science Foundation
4/1/14 → 3/31/15
Project: Research project
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Evolution Reloaded: From Artificial Genes to Novel Biological Functions
Hecht, M. H. (PI)
NSF - National Science Foundation
4/1/11 → 3/31/15
Project: Research project
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De Novo Proteins Template the Formation of Semiconductor Quantum Dots
Yao, Y., Wu, J., Hu, Y., Haubold, L., Uzosike, O., Cheng, G., Yao, N., Scholes, G. D., Hecht, M. H. & Spangler, L. C., Jun 25 2025, In: ACS Central Science. 11, 6, p. 983-993 11 p.Research output: Contribution to journal › Article › peer-review
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Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins
Schnettler, J. D., Wang, M. S., Gantz, M., Bunzel, H. A., Karas, C., Hollfelder, F. & Hecht, M. H., Jul 2024, In: Nature chemistry. 16, 7, p. 1200-1208 9 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Crystal structure and activity of a de novo enzyme, ferric enterobactin esterase Syn-F4
Kurihara, K., Umezawa, K., Donnelly, A. E., Sperling, B., Liao, G., Hecht, M. H. & Arai, R., Sep 19 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 38, e2218281120.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
A de novo protein catalyzes the synthesis of semiconductor quantum dots
Spangler, L. C., Yao, Y., Cheng, G., Yao, N., Chari, S. L., Scholes, G. D. & Hecht, M. H., Dec 20 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 51, e2204050119.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
New biological method for producing semiconductor quantum dots using de novo proteins
Hecht, M. (Inventor), Chari, S. (Inventor) & Spangler, L. (Inventor), Jun 15 2022Research output: Innovation