Joshua Akey

Saha, S., Khan, N., Comi, T., Verhagen, A., Sasmal, A., Diaz, S., Yu, H., Chen, X., Akey, J. M., Frank, M., Gagneux, P. & Varki, A., Aug 1 2022, In: Molecular biology and evolution. 39, 8, msac151.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Once-daily feeding is associated with better health in companion dogs: results from the Dog Aging Project

Dog Aging Project Consortium, Jun 2022, In: GeroScience. 44, 3, p. 1779-1790 12 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Purpose, Partnership, and Possibilities: The Implementation of the Dog Aging Project Biobank

Mouttham, L., Castelhano, M. G., Akey, J. M., Benton, B., Borenstein, E., Castelhano, M. G., Coleman, A. E., Creevy, K. E., Crowder, K., Dunbar, M. D., Ernst, H. R., Fajt, V. R., Fitzpatrick, A. L., Garrison, S. J., Herndon, R. S., Jaramilla, D., Jeffery, U., Jonlin, E. C., Kaeberlein, M., Karlsson, E. K., & 14 othersKerr, K. F., Levine, J. M., Ma, J., McClelland, R. L., Prescott, J. O., Promislow, D. E. L., Ruple, A., Schwartz, S. M., Shrager, S., Snyder-Mackler, N., Tinkle, A. K., Tolbert, M. K., Urfer, S. R. & Wilfond, B. S., Jan 1 2022, In: Biomarker Insights. 17

Research output: Contribution to journal › Article › peer-review

Open Access

The contribution of Neanderthal introgression to modern human traits

Reilly, P. F., Tjahjadi, A., Miller, S. L., Akey, J. M. & Tucci, S., Sep 26 2022, In: Current Biology. 32, 18, p. R970-R983

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

2021

Deep sequencing of 1320 genes reveals the landscape of protein-truncating variants and their contribution to psoriasis in 19,973 Chinese individuals

Xu, H., Zhen, Q., Bai, M., Fang, L., Zhang, Y., Li, B., Ge, H., Moon, S., Chen, W., Fu, W., Xu, Q., Zhou, Y., Yu, Y., Lin, L., Yong, L., Zhang, T., Chen, S., Liu, S., Zhang, H., Chen, R., & 8 othersCao, L., Zhang, Y., Zhang, R., Yang, H., Hu, X., Akey, J. M., Jin, X. & Sun, L., Jul 2021, In: Genome Research. 31, 7, p. 1150-1158 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Natural selection, genetic variation, and human diversity

Emery, L. S. & Akey, J. M., Apr 14 2021, Human Population Genomics: Introduction to Essential Concepts and Applications. Springer International Publishing, p. 205-234 30 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease

GTEx Consortium, May 13 2021, In: Cell. 184, 10, p. 2633-2648.e19

Research output: Contribution to journal › Article › peer-review

Open Access

59 Scopus citations

2020

A Quantitative Proteome Map of the Human Body

GTEx Consortium, Oct 1 2020, In: Cell. 183, 1, p. 269-283.e19

Research output: Contribution to journal › Article › peer-review

Open Access

149 Scopus citations

A vast resource of allelic expression data spanning human tissues

Castel, S. E., Aguet, F., Mohammadi, P., Aguet, F., Anand, S., Ardlie, K. G., Gabriel, S., Getz, G. A., Graubert, A., Hadley, K., Handsaker, R. E., Huang, K. H., Kashin, S., Li, X., MacArthur, D. G., Meier, S. R., Nedzel, J. L., Nguyen, D. T., Segrè, A. V., Todres, E., & 180 othersAguet, F., Anand, S., Ardlie, K. G., Balliu, B., Barbeira, A. N., Battle, A., Bonazzola, R., Brown, A., Brown, C. D., Castel, S. E., Conrad, D. F., Cotter, D. J., Cox, N., Das, S., De Goede, O. M., Dermitzakis, E. T., Einson, J., Engelhardt, B. E., Eskin, E., Eulalio, T. Y., Ferraro, N. M., Flynn, E. D., Fresard, L., Gamazon, E. R., Garrido-Martín, D., Gay, N. R., Gloudemans, M. J., Graubert, A., Guigó, R., Hadley, K., Hame, A. R., Handsaker, R. E., He, Y., Hoffman, P. J., Hormozdiari, F., Hou, L., Huang, K. H., Im, H. K., Jo, B., Kasela, S., Kashin, S., Kellis, M., Kim-Hellmuth, S., Kwong, A., Lappalainen, T., Li, X., Li, X., Liang, Y., Mangul, S., Meier, S. R., Mohammadi, P., Montgomery, S. B., Muñoz-Aguirre, M., Nachun, D. C., Nedzel, J. L., Nguyen, D. T., Nobel, A. B., Oliva, M., Park, Y. S., Park, Y., Parsana, P., Rao, A. S., Reverter, F., Rouhana, J. M., Sabatti, C., Saha, A., Segrè, A. V., Skol, A. D., Stephens, M., Stranger, B. E., Strober, B. J., Teran, N. A., Todres, E., Viñuela, A., Wang, G., Wen, X., Wright, F., Wucher, V., Zou, Y., Ferreira, P. G., Li, G., Melé, M., Yeger-Lotem, E., Barcus, M. E., Bradbury, D., Krubit, T., McLean, J. A., Qi, L., Robinson, K., Roche, N. V., Smith, A. M., Sobin, L., Tabor, D. E., Undale, A., Bridge, J., Brigham, L. E., Foster, B. A., Gillard, B. M., Hasz, R., Hunter, M., Johns, C., Johnson, M., Karasik, E., Kopen, G., Leinweber, W. F., McDonald, A., Moser, M. T., Myer, K., Ramsey, K. D., Roe, B., Shad, S., Thomas, J. A., Walters, G., Washington, M., Wheeler, J., Jewell, S. D., Rohrer, D. C., Valley, D. R., Davis, D. A., Mash, D. C., Barcus, M. E., Branton, P. A., Sobin, L., Barker, L. K., Gardiner, H. M., Mosavel, M., Siminoff, L. A., Flicek, P., Haeussler, M., Juettemann, T., Kent, W. J., Lee, C. M., Powell, C. C., Rosenbloom, K. R., Ruffier, M., Sheppard, D., Taylor, K., Trevanion, S. J., Zerbino, D. R., Abell, N. S., Akey, J., Chen, L., Demanelis, K., Doherty, J. A., Feinberg, A. P., Hansen, K. D., Hickey, P. F., Hou, L., Jasmine, F., Jiang, L., Kaul, R., Kibriya, M. G., Li, J. B., Li, Q., Lin, S., Linder, S. E., Montgomery, S. B., Oliva, M., Park, Y., Pierce, B. L., Rizzardi, L. F., Skol, A. D., Smith, K. S., Snyder, M., Stamatoyannopoulos, J., Stranger, B. E., Tang, H., Wang, M., Branton, P. A., Carithers, L. J., Guan, P., Koester, S. E., Little, A. R., Moore, H. M., Nierras, C. R., Rao, A. K., Vaught, J. B., Volpi, S., Ardlie, K. G. & Lappalainen, T., Sep 11 2020, In: Genome biology. 21, 1, 234.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Cell type–specific genetic regulation of gene expression across human tissues

GTEx Consortium, Sep 2020, In: Science. 369, 6509, eaaz8528.

Research output: Contribution to journal › Article › peer-review

Open Access

117 Scopus citations

Editorial overview: Evolutionary genomics – from molecular mechanisms to phenotypes to populations

Akey, J. & Tishkoff, S., Jun 2020, In: Current Opinion in Genetics and Development. 62, p. iii-iv

Research output: Contribution to journal › Editorial › peer-review

Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Chen, L., Wolf, A. B., Fu, W., Li, L. & Akey, J. M., Feb 20 2020, In: Cell. 180, 4, p. 677-687.e16

Research output: Contribution to journal › Article › peer-review

Open Access

102 Scopus citations

Implications of localized charge for human influenza A H1N1 hemagglutinin evolution: Insights from deep mutational scans

Saad-Roy, C. M., Arinaminpathy, N., Wingreen, N. S., Levin, S. A., Akey, J. M. & Grenfell, B. T., Jun 2020, In: PLoS computational biology. 16, 6, e1007892.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

The GTEx Consortium atlas of genetic regulatory effects across human tissues

The GTEx Consortium, Sep 1 2020, In: Science. 369, 6509, p. 1318-1330 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1239 Scopus citations

Transcriptomic signatures across human tissues identify functional rare genetic variation

TOPMed Lipids Working Group & GTEx Consortium, Sep 11 2020, In: Science. 369, 6509, eaaz5900.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

2019

Statistical methods to detect archaic admixture and identify introgressed sequences

Li, L. & Akey, J. M., Jul 29 2019, Handbook of Statistical Genomics. wiley, Vol. 1. p. 275-293 19 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

The long walk to African genomics

Tucci, S. & Akey, J. M., Jun 27 2019, In: Genome biology. 20, 1, 130.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2018

Analysis of Human Sequence Data Reveals Two Pulses of Archaic Denisovan Admixture

Browning, S. R., Browning, B. L., Zhou, Y., Tucci, S. & Akey, J. M., Mar 22 2018, In: Cell. 173, 1, p. 53-61.e9

Research output: Contribution to journal › Article › peer-review

Open Access

185 Scopus citations

Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia

Tucci, S., Vohr, S. H., McCoy, R. C., Vernot, B., Robinson, M. R., Barbieri, C., Nelson, B. J., Fu, W., Purnomo, G. A., Sudoyo, H., Eichler, E. E., Barbujani, G., Visscher, P. M., Akey, J. M. & Green, R. E., Aug 3 2018, In: Science. 361, 6401, p. 511-516 6 p.

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Evolution of dnaase i hypersensitive sites in mhc regulatory regions of primates

Jin, Y., Gittelman, R. M., Lu, Y., Liu, X., Li, M. D., Ling, F. & Akey, J. M., Jun 2018, In: Genetics. 209, 2, p. 579-589 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics

Barbeira, A. N., Dickinson, S. P., Bonazzola, R., Zheng, J., Wheeler, H. E., Torres, J. M., Torstenson, E. S., Shah, K. P., Garcia, T., Edwards, T. L., Stahl, E. A., Huckins, L. M., Aguet, F., Ardlie, K. G., Cummings, B. B., Gelfand, E. T., Getz, G., Hadley, K., Handsaker, R. E., Huang, K. H., & 225 othersKashin, S., Karczewski, K. J., Lek, M., Li, X., MacArthur, D. G., Nedzel, J. L., Nguyen, D. T., Noble, M. S., Segrè, A. V., Trowbridge, C. A., Tukiainen, T., Abell, N. S., Balliu, B., Barshir, R., Basha, O., Battle, A., Bogu, G. K., Brown, A., Brown, C. D., Castel, S. E., Chen, L. S., Chiang, C., Conrad, D. F., Damani, F. N., Davis, J. R., Delaneau, O., Dermitzakis, E. T., Engelhardt Martin, B., Eskin, E., Ferreira, P. G., Frésard, L., Gamazon, E. R., Garrido-Martín, D., Gewirtz, A. D. H., Gliner, G., Gloudemans, M. J., Guigo, R., Hall, I. M., Han, B., He, Y., Hormozdiari, F., Howald, C., Jo, B., Kang, E. Y., Kim, Y., Kim-Hellmuth, S., Lappalainen, T., Li, G., Li, X., Liu, B., Mangul, S., McCarthy, M. I., McDowell, I. C., Mohammadi, P., Monlong, J., Montgomery, S. B., Muñoz-Aguirre, M., Ndungu, A. W., Nobel, A. B., Oliva, M., Ongen, H., Palowitch, J. J., Panousis, N., Papasaikas, P., Park, Y. S., Parsana, P., Payne, A. J., Peterson, C. B., Quan, J., Reverter, F., Sabatti, C., Saha, A., Sammeth, M., Scott, A. J., Shabalin, A. A., Sodaei, R., Stephens, M., Stranger, B. E., Strober, B. J., Sul, J. H., Tsang, E. K., Urbut, S., Van De Bunt, M., Wang, G., Wen, X., Wright, F. A., Xi, H. S., Yeger-Lotem, E., Zappala, Z., Zaugg, J. B., Zhou, Y. H., Akey, J., Bates, D., Chan, J., Claussnitzer, M., Demanelis, K., Diegel, M., Doherty, J. A., Feinberg, A. P., Fernando, M. S., Halow, J., Hansen, K. D., Haugen, E., Hickey, P. F., Hou, L., Jasmine, F., Jian, R., Jiang, L., Johnson, A., Kaul, R., Kellis, M., Kibriya, M. G., Lee, K., Li, J. B., Li, Q., Lin, J., Lin, S., Linder, S., Linke, C., Liu, Y., Maurano, M. T., Molinie, B., Nelson, J., Neri, F. J., Park, Y., Pierce, B. L., Rinaldi, N. J., Rizzardi, L. F., Sandstrom, R., Skol, A., Smith, K. S., Snyder, M. P., Stamatoyannopoulos, J., Tang, H., Wang, L., Wang, M., Van Wittenberghe, N., Wu, F., Zhang, R., Nierras, C. R., Branton, P. A., Carithers, L. J., Guan, P., Moore, H. M., Rao, A., Vaught, J. B., Gould, S. E., Lockart, N. C., Martin, C., Struewing, J. P., Volpi, S., Addington, A. M., Koester, S. E., Little, A. R., Brigham, L. E., Hasz, R., Hunter, M., Johns, C., Johnson, M., Kopen, G., Leinweber, W. F., Lonsdale, J. T., McDonald, A., Mestichelli, B., Myer, K., Roe, B., Salvatore, M., Shad, S., Thomas, J. A., Walters, G., Washington, M., Wheeler, J., Bridge, J., Foster, B. A., Gillard, B. M., Karasik, E., Kumar, R., Miklos, M., Moser, M. T., Jewell, S. D., Montroy, R. G., Rohrer, D. C., Valley, D. R., Davis, D. A., Mash, D. C., Undale, A. H., Smith, A. M., Tabor, D. E., Roche, N. V., McLean, J. A., Vatanian, N., Robinson, K. L., Sobin, L., Barcus, M. E., Valentino, K. M., Qi, L., Hunter, S., Hariharan, P., Singh, S., Um, K. S., Matose, T., Tomaszewski, M. M., Barker, L. K., Mosavel, M., Siminoff, L. A., Traino, H. M., Flicek, P., Juettemann, T., Ruffier, M., Sheppard, D., Taylor, K., Trevanion, S. J., Zerbino, D. R., Craft, B., Goldman, M., Haeussler, M., Kent, W. J., Lee, C. M., Paten, B., Rosenbloom, K. R., Vivian, J., Zhu, J., Nicolae, D. L., Cox, N. J. & Im, H. K., Dec 1 2018, In: Nature communications. 9, 1, 1825.

Research output: Contribution to journal › Article › peer-review

Open Access

452 Scopus citations

Massive variation of short tandem repeats with functional consequences across strains of Arabidopsis thaliana

Press, M. O., McCoy, R. C., Hall, A. N., Akey, J. M. & Queitsch, C., Aug 2018, In: Genome Research. 28, 8, p. 1169-1178 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Optimized distributed systems achieve significant performance improvement on sorted merging of massive VCF files

CAAPA consortium, Jun 1 2018, In: GigaScience. 7, 6, giy052.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

Outstanding questions in the study of archaic hominin admixture

Wolf, A. B. & Akey, J. M., May 2018, In: PLoS genetics. 14, 5, e1007349.

Research output: Contribution to journal › Review article › peer-review

Open Access

35 Scopus citations

Rare loss of function variants in candidate genes and risk of colorectal cancer

NHLBI GO Exome Sequencing Project, Pulmonary Arterial Hypertension (PAH), Severe Asthma Research Program (SARP), Women’s Health Initiative (WHI), Anthropometry Project Team, Blood Count/Hematology Project Team, Blood Pressure Project Team, Data Flow Working Group, Early MI Project Team, ELSI Working Group, Executive Committee, Family Study Project Team, Lipids Project Team, Lung Project Team, Personal Genomics Project Team, Phenotype and Harmonization Working Group, Population Genetics and Statistical Analysis Working Group, Publications and Presentations Working Group, Quantitative Analysis Ad Hoc Task Group, Sequencing and Genotyping Working Group, & 15 othersSteering Committee, Stroke Project Team, Structural Variation Working Group, Subclinical/Quantitative Project Team, Acute Lung Injury (ALI), Atherosclerosis Risk in Communities (ARIC), Cardiovascular Health Study (CHS), Chronic Obstructive Pulmonary Disease (COPDGene), Coronary Artery Risk Development in Young Adults (CARDIA), Cystic Fibrosis (CF), Early Pseudomonas Infection Control (EPIC), Framingham Heart Study (FHS), Jackson Heart Study (JHS), Lung Health Study (LHS) & Multi-Ethnic Study of Atherosclerosis (MESA), Oct 1 2018, In: Human Genetics. 137, 10, p. 795-806 12 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2017

Dynamic landscape and regulation of RNA editing in mammals

GTEx Consortium, Oct 11 2017, In: Nature. 550, 7675, p. 249-254 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

348 Scopus citations

Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease

Stranger, B. E., Brigham, L. E., Hasz, R., Hunter, M., Johns, C., Johnson, M., Kopen, G., Leinweber, W. F., Lonsdale, J. T., McDonald, A., Mestichelli, B., Myer, K., Roe, B., Salvatore, M., Shad, S., Thomas, J. A., Walters, G., Washington, M., Wheeler, J., Bridge, J., & 75 othersFoster, B. A., Gillard, B. M., Karasik, E., Kumar, R., Miklos, M., Moser, M. T., Jewell, S. D., Montroy, R. G., Rohrer, D. C., Valley, D. R., Davis, D. A., Mash, D. C., Gould, S. E., Guan, P., Koester, S., Little, A. R., Martin, C., Moore, H. M., Rao, A., Struewing, J. P., Volpi, S., Hansen, K. D., Hickey, P. F., Rizzardi, L. F., Hou, L., Liu, Y., Molinie, B., Park, Y., Rinaldi, N., Wang, L., Wittenberghe, N., Claussnitzer, M., Gelfand, E. T., Li, Q., Linder, S., Zhang, R., Smith, K. S., Tsang, E. K., Chen, L. S., Demanelis, K., Doherty, J. A., Farzana, J., Kibriya, M. G., Jiang, L., Lin, S., Wang, M., Jian, R., Li, X., Chan, J., Bates, D., Diegel, M., Halow, J., Haugen, E., Johnson, A., Kaul, R., Lee, K., Maurano, M. T., Nelson, J., Neri, F. J., Sandstrom, R., Fernando, M. S., Linke, C., Oliva, M., Skol, A., Wu, F., Akey, J. M., Feinberg, A. P., Billy, J. L., Pierce, B. L., Stamatoyannopoulos, J. A., Tang, H., Ardlie, K. G., Kellis, M., Snyder, M. P. & Montgomery, S. B., Dec 1 2017, In: Nature Genetics. 49, 12, p. 1664-1670 7 p.

Research output: Contribution to journal › Review article › peer-review

126 Scopus citations

Genetic effects on gene expression across human tissues

GTEx Consortium, Oct 11 2017, In: Nature. 550, 7675, p. 204-213 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2144 Scopus citations

Human RECQ Helicase Pathogenic Variants, Population Variation and “Missing” Diseases

Fu, W., Ligabue, A., Rogers, K. J., Akey, J. M. & Monnat, R. J., Feb 1 2017, In: Human Mutation. 38, 2, p. 193-203 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis

The GTEx Consortium, Nov 2017, In: Genome Research. 27, 11, p. 1859-1871 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome

Consortia CAAPA Consortium, 2017, In: Scientific reports. 7, 46398.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Impacts of Neanderthal-Introgressed Sequences on the Landscape of Human Gene Expression

McCoy, R. C., Wakefield, J. & Akey, J. M., Feb 23 2017, In: Cell. 168, 5, p. 916-927.e12

Research output: Contribution to journal › Article › peer-review

Open Access

90 Scopus citations

Improving genetic diagnosis in Mendelian disease with transcriptome sequencing

Genotype-Tissue Expression Consortium, National Institutes of Health (NIH) Common Fund, iospecimen Collection Source Site-National Disease Research Interchange, Biospecimen Collection Source Site-Roswell Park Cancer Institute, Biospecimen Core Resource-Van Andel Research Institute, Brain Bank Repository-University of Miami, Leidos Biomedical Project Management, Ethical, Legal, and Social Implications Study, Genome Browser Data Integration, and Visualization-European Bioinformatics Institute, Genome Browser Data Integration and Visualization-Genomics Institute, University of California, Santa Cruz:, LDACC-Analysis Working Group (AWG), Funded Statistical Methods groups-AWG, Enhancing GTEx funded Group, NIH/NHGRI, NIH/NCI, NIH/NIMH, NIH/NIDA & Other members of the AWG, Apr 19 2017, In: Science Translational Medicine. 9, 386, eaal5209.

Research output: Contribution to journal › Article › peer-review

421 Scopus citations

Landscape of X chromosome inactivation across human tissues

GTEx Consortium, Oct 11 2017, In: Nature. 550, 7675, p. 244-248 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

529 Scopus citations

Selection plays the hand it was dealt: Evidence that human adaptation commonly targets standing genetic variation

McCoy, R. C. & Akey, J. M., Aug 1 2017, In: Genome biology. 18, 1, 139.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

The impact of rare variation on gene expression across tissues

GTEx Consortium, Oct 11 2017, In: Nature. 550, 7675, p. 239-243 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

142 Scopus citations

Tracing the peopling of the world through genomics

Nielsen, R., Akey, J. M., Jakobsson, M., Pritchard, J. K., Tishkoff, S. & Willerslev, E., Jan 18 2017, In: Nature. 541, 7637, p. 302-310 9 p.

Research output: Contribution to journal › Review article › peer-review

344 Scopus citations

2016

A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome

Mathias, R. A., Taub, M. A., Gignoux, C. R., Fu, W., Musharoff, S., O'Connor, T. D., Vergara, C., Torgerson, D. G., Pino-Yanes, M., Shringarpure, S. S., Huang, L., Rafaels, N., Boorgula, M. P., Johnston, H. R., Ortega, V. E., Levin, A. M., Song, W., Torres, R., Padhukasahasram, B., Eng, C., & 42 othersMejia-Mejia, D. A., Ferguson, T., Qin, Z. S., Scott, A. F., Yazdanbakhsh, M., Wilson, J. G., Marrugo, J., Lange, L. A., Kumar, R., Avila, P. C., Williams, L. K., Watson, H., Ware, L. B., Olopade, C., Olopade, O., Oliveira, R., Ober, C., Nicolae, D. L., Meyers, D., Mayorga, A., Knight-Madden, J., Hartert, T., Hansel, N. N., Foreman, M. G., Ford, J. G., Faruque, M. U., Dunston, G. M., Caraballo, L., Burchard, E. G., Bleecker, E., Araujo, M. I., Herrera-Paz, E. F., Gietzen, K., Grus, W. E., Bamshad, M., Bustamante, C. D., Kenny, E. E., Hernandez, R. D., Beaty, T. H., Ruczinski, I., Akey, J. & Barnes, K. C., Oct 11 2016, In: Nature communications. 7, 12522.

Research output: Contribution to journal › Article › peer-review

Open Access

99 Scopus citations

A flexible method for estimating the fraction of fitness influencing mutations from large sequencing data sets

Moon, S. & Akey, J. M., Jun 2016, In: Genome Research. 26, 6, p. 834-843 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Archaic Hominin Admixture Facilitated Adaptation to Out-of-Africa Environments

Gittelman, R. M., Schraiber, J. G., Vernot, B., Mikacenic, C., Wurfel, M. M. & Akey, J. M., Dec 19 2016, In: Current Biology. 26, 24, p. 3375-3382 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

104 Scopus citations

Detecting sources of transcriptional heterogeneity in large-scale RNA-seq data sets

Searle, B. C., Gittelman, R. M., Manor, O. & Akey, J. M., Dec 2016, In: Genetics. 204, 4, p. 1391-1396 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Editorial overview: Genetics of human origin: New horizons in human population genetics

Akey, J. M. & Di Rienzo, A., Dec 1 2016, In: Current Opinion in Genetics and Development. 41, p. v-vi

Research output: Contribution to journal › Editorial › peer-review

Emergence of a Homo sapiens-specific gene family and chromosome 16p11.2 CNV susceptibility

Nuttle, X., Giannuzzi, G., Duyzend, M. H., Schraiber, J. G., Narvaiza, I., Sudmant, P. H., Penn, O., Chiatante, G., Malig, M., Huddleston, J., Benner, C., Camponeschi, F., Ciofi-Baffoni, S., Stessman, H. A. F., Marchetto, M. C. N., Denman, L., Harshman, L., Baker, C., Raja, A., Penewit, K., & 10 othersJanke, N., Joyce Tang, W., Ventura, M., Banci, L., Antonacci, F., Akey, J. M., Amemiya, C. T., Gage, F. H., Reymond, A. & Eichler, E. E., Aug 3 2016, In: Nature. 536, 7615, p. 205-209 5 p.

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals

Vernot, B., Tucci, S., Kelso, J., Schraiber, J. G., Wolf, A. B., Gittelman, R. M., Dannemann, M., Grote, S., McCoy, R. C., Norton, H., Scheinfeldt, L. B., Merriwether, D. A., Koki, G., Friedlaender, J. S., Wakefield, J., Pääbo, S. & Akey, J. M., Apr 8 2016, In: Science. 352, 6282, p. 235-239 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

262 Scopus citations

Human Diversity in a Cell Surface Receptor that Inhibits Autophagy

Chaudhary, A., Leite, M., Kulasekara, B. R., Altura, M. A., Ogahara, C., Weiss, E., Fu, W., Blanc, M. P., O'Keeffe, M., Terhorst, C., Akey, J. M. & Miller, S. I., Jul 25 2016, In: Current Biology. 26, 14, p. 1791-1801 11 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Joshua Akey

Research output

Search results