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Dive into the research topics where Jared E. Toettcher is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Optogenetics and biosensors for dissecting cellular decision-making
Toettcher, J. E. (PI)
6/1/26 → 5/31/31
Project: Research project
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Characterizing the interpretation and generation of Erk signaling dynamics using high-throughput genetics
Toettcher, J. E. (PI)
7/1/24 → 6/30/27
Project: Research project
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Optogenetic dissection of Erk signal interpretation in early embryogenesis
Toettcher, J. E. (PI)
4/1/23 → 3/31/25
Project: Research project
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A new class of biosensors for detecting signaling dynamics without live-cell microscopy
Toettcher, J. E. (PI)
9/22/22 → 8/31/26
Project: Research project
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Cracking the signaling code: how ERK activity dynamics coordinate gene expression and differentiation in keratinocytes
Toettcher, J. E. (PI)
8/1/19 → 7/31/21
Project: Research project
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An optogenetic smart microscopy platform reveals signaling dynamics-dependent control over collective cell migration
Oatman, H. R., Lad, B. C., Nguyen, L., Gubbens, J. H. & Toettcher, J. E., Sep 16 2026, In: Cell Systems. 17, 9, 101674.Research output: Contribution to journal › Article › peer-review
Open Access -
CD44 restricts EGFR mobility to polarize cytoskeletal signalling modules driving bleb-based migration
Jha, A., Chandra, A., Farahani, P. E., Toettcher, J. E., Pasapera, A. M., Haugh, J. M. & Waterman, C. M., Jul 2026, In: Nature cell biology. 28, 7, p. 1408-1423 16 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Design and optimization of a kinase-controlled allosteric switch
Cao, Q. & Toettcher, J. E., Aug 2026, In: Nature Methods. 23, 8, p. 1540-1552 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Efficient genome editing with chimeric oligonucleotide-directed editing
Nguyen, L. T., Rakestraw, N. R., Pizzano, B. L. M., Iyyappan, R., Young, C. B., Huang, Y., Beerensson, K. T., Fang, A., Antal, S. G., Anamisis, K. V., Peggs, C. M. D., Yan, J., Jing, Y., Lewis, J. G., Burdine, R. D., Adamson, B., Jiang, Z., Toettcher, J. E., Myhrvold, C. & Jain, P. K., Dec 2026, In: Nature communications. 17, 1, 5051.Research output: Contribution to journal › Article › peer-review
Open Access -
Lights up on the embryonic dance: tools and applications of optogenetics in developmental biology
Gao, Y., Ho, E. K. & Toettcher, J. E., May 1 2026, In: Genes and Development. 40, 9-10, p. 607-626 20 p.Research output: Contribution to journal › Review article › peer-review
Open Access