George Ghanim

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20192025

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  • Active telomere elongation by a subclass of cancer-associated POT1 mutations

    Martin, A., Schabort, J., Bartke-Croughan, R., Tran, S., Preetham, A., Lu, R., Ho, R., Gao, J., Jenkins, S., Boyle, J., Ghanim, G. E., Jagota, M., Song, Y. S., Li, H. & Hockemeyer, D., Apr 1 2025, In: Genes and Development. 39, 7-8, p. 445-462 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization

    Balch, S., Sekne, Z., Franco-Echevarría, E., Ludzia, P., Kretsch, R. C., Sun, W., Yu, H., Ghanim, G. E., Thorkelsson, S., Ding, Y., Das, R. & Nguyen, T. H. D., Jul 10 2025, In: Science. 389, 6756, eadr5817.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • RNA-Puzzles Round V: blind predictions of 23 RNA structures

    Bu, F., Adam, Y., Adamiak, R. W., Antczak, M., de Aquino, B. R. H., Badepally, N. G., Batey, R. T., Baulin, E. F., Boinski, P., Boniecki, M. J., Bujnicki, J. M., Carpenter, K. A., Chacon, J., Chen, S. J., Chiu, W., Cordero, P., Das, N. K., Das, R., Dawson, W. K. & DiMaio, F. & 79 others, Ding, F., Dock-Bregeon, A. C., Dokholyan, N. V., Dror, R. O., Dunin-Horkawicz, S., Eismann, S., Ennifar, E., Esmaeeli, R., Farsani, M. A., Ferré-D’Amaré, A. R., Geniesse, C., Ghanim, G. E., Guzman, H. V., Hood, I. V., Huang, L., Jain, D. S., Jaryani, F., Jin, L., Joshi, A., Karelina, M., Kieft, J. S., Kladwang, W., Kmiecik, S., Koirala, D., Kollmann, M., Kretsch, R. C., Kurciński, M., Li, J., Li, S., Magnus, M., Masquida, B., Moafinejad, S. N., Mondal, A., Mukherjee, S., Nguyen, T. H. D., Nikolaev, G., Nithin, C., Nye, G., Pandaranadar Jeyeram, I. P. N., Perez, A., Pham, P., Piccirilli, J. A., Pilla, S. P., Pluta, R., Poblete, S., Ponce-Salvatierra, A., Popenda, M., Popenda, L., Pucci, F., Rangan, R., Ray, A., Ren, A., Sarzynska, J., Sha, C. M., Stefaniak, F., Su, Z., Suddala, K. C., Szachniuk, M., Townshend, R., Trachman, R. J., Wang, J., Wang, W., Watkins, A., Wirecki, T. K., Xiao, Y., Xiong, P., Xiong, Y., Yang, J., Yesselman, J. D., Zhang, J., Zhang, Y., Zhang, Z., Zhou, Y., Zok, T., Zhang, D., Zhang, S., Żyła, A., Westhof, E. & Miao, Z., Feb 2025, In: Nature Methods. 22, 2, p. 399-411 13 p., 2871.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Structural mechanism of LINE-1 target-primed reverse transcription

    Ghanim, G. E., Hu, H., Boulanger, J. & Nguyen, T. H. D., Apr 25 2025, In: Science. 388, 6745, eads6055.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • 2.7 Å cryo-EM structure of human telomerase H/ACA ribonucleoprotein

    Ghanim, G. E., Sekne, Z., Balch, S., van Roon, A. M. M. & Nguyen, T. H. D., Dec 2024, In: Nature communications. 15, 1, 746.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations