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Dive into the research topics where Frederick McLaury Hughson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Structural Analysis of Membrane Tethering and Fusion Proteins
Hughson, F. M. (PI)
3/15/21 → 2/28/26
Project: Research project
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A Structural and Mechanistic Basis for COPI-Coated Vesicle Tethering by the Dsl1 Multisubunit Tethering Complex
Hughson, F. M. (PI)
9/1/17 → 8/31/19
Project: Research project
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Structural Analysis of Membrane Tethering and Fusion Proteins
Hughson, F. M. (PI)
3/1/17 → 2/28/21
Project: Research project
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Structural Analysis of Golgi Trafficking Proteins
Hughson, F. M. (PI)
6/1/13 → 2/28/17
Project: Research project
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Manipulating Quorum Sensing to Control Bacterial Pathogenecity
Hughson, F. M. (PI)
4/1/12 → 3/31/14
Project: Research project
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Structure of a membrane tethering complex incorporating multiple SNAREs
DAmico, K. A., Stanton, A. E., Shirkey, J. D., Travis, S. M., Jeffrey, P. D. & Hughson, F. M., Feb 2024, In: Nature Structural and Molecular Biology. 31, 2, p. 246-254 9 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
The machinery of vesicle fusion
Stanton, A. E. & Hughson, F. M., Aug 2023, In: Current Opinion in Cell Biology. 83, 102191.Research output: Contribution to journal › Review article › peer-review
Open Access17 Scopus citations -
Chaperoning SNARE Folding and Assembly
Zhang, Y. & Hughson, F. M., Jun 20 2021, In: Annual review of biochemistry. 90, p. 581-603 23 p.Research output: Contribution to journal › Review article › peer-review
Open Access83 Scopus citations -
Cargo Release from Myosin V Requires the Convergence of Parallel Pathways that Phosphorylate and Ubiquitylate the Cargo Adaptor
Wong, S., Hepowit, N. L., Port, S. A., Yau, R. G., Peng, Y., Azad, N., Habib, A., Harpaz, N., Schuldiner, M., Hughson, F. M., MacGurn, J. A. & Weisman, L. S., Nov 16 2020, In: Current Biology. 30, 22, p. 4399-4412.e7Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1
Travis, S. M., DAmico, K., Yu, I. M., McMahon, C., Hamid, S., Ramirez-Arellano, G., Jeffrey, P. D. & Hughson, F. M., Jul 24 2020, In: Journal of Biological Chemistry. 295, 30, p. 10125-10135 11 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations