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David W.C. MacMillan

  • 33083 Citations
  • 92 h-Index
1995 …2022
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Fingerprint Dive into the research topics where David W.C. MacMillan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Catalysis Chemical Compounds
Aldehydes Medicine & Life Sciences
Catalysts Chemical Compounds
Amines Medicine & Life Sciences
Chemical activation Chemical Compounds
Ketones Chemical Compounds
Alkylation Medicine & Life Sciences
Alkenes Medicine & Life Sciences

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Projects 2010 2022

Photoredox-Enabled Applications of Primary Amines as Alkylating Reagents

MacMillan, D. W. C.

NIH NIGMS

8/1/19 → 7/31/22

Project: Research project

Amines

Photoredox Catalysis Applications in Organometallics and Chemical Biology

MacMillan, D. W. C.

NIH NIGMS

1/1/19 → 12/31/19

Project: Research project

Organometallics
Catalysis

New Strategies in Metallaphotoredox Catalysis

MacMillan, D. W. C.

NIH NIGMS

6/1/18 → 5/31/22

Project: Research project

Catalysis

Discovery, Invention and Development of New Bond Forming Reactions using Light

MacMillan, D. W. C.

Office of Naval Research

3/1/18 → 2/28/21

Project: Research project

Patents and inventions

Combining Nickel and Photoredox Catalysis

MacMillan, D. W. C.

NIH NIGMS

8/1/16 → 5/31/20

Project: Research project

Nickel
Catalysis

Research Output 1995 2019

A Metallaphotoredox Strategy for the Cross-Electrophile Coupling of α-Chloro Carbonyls with Aryl Halides

Chen, T. Q. & MacMillan, D. W. C., Oct 7 2019, In : Angewandte Chemie - International Edition. 58, 41, p. 14584-14588 5 p.

Research output: Contribution to journal › Article

Chlorides
Halogens
Acids
Nickel
Bromides
11 Citations (Scopus)

Copper-Catalyzed Trifluoromethylation of Alkyl Bromides

Kornfilt, D. J. P. & MacMillan, D. W. C., May 1 2019, In : Journal of the American Chemical Society. 141, 17, p. 6853-6858 6 p.

Research output: Contribution to journal › Article

Bromides
Copper
Bromine
Carbon
Electrons
3 Citations (Scopus)

Photoredox-catalyzed deoxyfluorination of activated alcohols with Selectfluor®

González-Esguevillas, M., Miró, J., Jeffrey, J. L. & MacMillan, D. W. C., Aug 9 2019, In : Tetrahedron. 75, 32, p. 4222-4227 6 p.

Research output: Contribution to journal › Article

Alcohols
Fluorine
Catalysis
Light
selectfluor
7 Citations (Scopus)

The Evolution of High-Throughput Experimentation in Pharmaceutical Development and Perspectives on the Future

Mennen, S. M., Alhambra, C., Allen, C. L., Barberis, M., Berritt, S., Brandt, T. A., Campbell, A. D., Castañón, J., Cherney, A. H., Christensen, M., Damon, D. B., Eugenio De Diego, J., García-Cerrada, S., García-Losada, P., Haro, R., Janey, J., Leitch, D. C., Li, L., Liu, F., Lobben, P. C. & 12 others, Macmillan, D. W. C., Magano, J., McInturff, E., Monfette, S., Post, R. J., Schultz, D., Sitter, B. J., Stevens, J. M., Strambeanu, I. I., Twilton, J., Wang, K. & Zajac, M. A., Jun 21 2019, In : Organic Process Research and Development. 23, 6, p. 1213-1242 30 p.

Research output: Contribution to journal › Article

experimentation
Throughput
Pharmaceutical Preparations
Screening
Industry
64 Citations (Scopus)

A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes

Le, C., Chen, T. Q., Liang, T., Zhang, P. & MacMillan, D. W. C., Jun 1 2018, In : Science. 360, 6392, p. 1010-1014 5 p.

Research output: Contribution to journal › Article

Copper
Catalysis
Halogens
Bromides