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Research Output 1981 2019

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Article
2019
5 Citations (Scopus)

CaImAn an open source tool for scalable calcium imaging data analysis

Giovannucci, A., Friedrich, J., Gunn, P., Kalfon, J., Brown, B. L., Koay, S. A., Taxidis, J., Najafi, F., Gauthier, J. L., Zhou, P., Khakh, B. S., Tank, D. W., Chklovskii, D. B. & Pnevmatikakis, E. A., Jan 17 2019, In : eLife. 8

Research output: Contribution to journalArticle

Alligators and Crocodiles
Photons
Calcium
Imaging techniques
Cluster computing

Cerebellar disruption impairs working memory during evidence accumulation

Deverett, B., Kislin, M., Tank, D. W. & Wang, S. S-H., Dec 1 2019, In : Nature communications. 10, 1, 3128.

Research output: Contribution to journalArticle

Open Access
Short-Term Memory
Optogenetics
Data storage equipment
Purkinje Cells
cerebellum
2018
17 Citations (Scopus)

A Dedicated Population for Reward Coding in the Hippocampus

Gauthier, J. L. & Tank, D. W., Jul 11 2018, In : Neuron. 99, 1, p. 179-193.e7

Research output: Contribution to journalArticle

Reward
Hippocampus
Population
Neurons
7 Citations (Scopus)

A Map-like Micro-Organization of Grid Cells in the Medial Entorhinal Cortex

Gu, Y., Lewallen, S., Kinkhabwala, A. A., Domnisoru, C., Yoon, K., Gauthier, J. L., Fiete, I. R. & Tank, D. W., Oct 18 2018, In : Cell. 175, 3, p. 736-750.e30

Research output: Contribution to journalArticle

Entorhinal Cortex
Navigation
Tuning
Networks (circuits)
Topography
9 Citations (Scopus)

An accumulation-of-evidence task using visual pulses for mice navigating in virtual reality

Pinto, L., Koay, S. A., Engelhard, B., Yoon, A. M., Deverett, B., Thiberge, S. Y., Witten, I. B., Tank, D. W. & Brody, C. D., Mar 6 2018, In : Frontiers in Behavioral Neuroscience. 12, 36.

Research output: Contribution to journalArticle

Cues
Decision Making
Reward
Arm
Head
9 Citations (Scopus)

Imaging Cortical Dynamics in GCaMP Transgenic Rats with a Head-Mounted Widefield Macroscope

Scott, B. B., Thiberge, S. Y., Guo, C., Tervo, D. G. R., Brody, C. D., Karpova, A. Y. & Tank, D. W., Dec 5 2018, In : Neuron. 100, 5, p. 1045-1058.e5

Research output: Contribution to journalArticle

Transgenic Rats
Neuroimaging
Head
Calcium
Technology
2017
10 Citations (Scopus)

Collective Behavior of Place and Non-place Neurons in the Hippocampal Network

Meshulam, L., Gauthier, J. L., Brody, C. D., Tank, D. W. & Bialek, W., Dec 6 2017, In : Neuron. 96, 5, p. 1178-1191.e4

Research output: Contribution to journalArticle

Neurons
Hippocampus
Population
Optical Imaging
Entropy
20 Citations (Scopus)

Fronto-parietal Cortical Circuits Encode Accumulated Evidence with a Diversity of Timescales

Scott, B. B., Constantinople, C. M., Akrami, A., Hanks, T. D., Brody, C. D. & Tank, D. W., Jul 19 2017, In : Neuron. 95, 2, p. 385-398.e5

Research output: Contribution to journalArticle

Parietal Lobe
Neurons
Decision Making
Frontal Lobe
Short-Term Memory
98 Citations (Scopus)

Mapping of a non-spatial dimension by the hippocampal-entorhinal circuit

Aronov, D., Nevers, R. & Tank, D. W., Mar 29 2017, In : Nature. 543, 7647, p. 719-722 4 p.

Research output: Contribution to journalArticle

Neurons
Entorhinal Cortex
Hippocampus
Head
Spatial Navigation
30 Citations (Scopus)

Volumetric two-photon imaging of neurons using stereoscopy (vtwins)

Song, A., Charles, A. S., Koay, S. A., Gauthier, J. L., Thiberge, S. Y., Pillow, J. W. & Tank, D. W., Mar 20 2017, In : Nature Methods. 14, 4, p. 420-426 7 p.

Research output: Contribution to journalArticle

Photons
Neurons
Imaging techniques
Calcium
Visual Cortex
2016
14 Citations (Scopus)

Grid Cell Responses in 1D Environments Assessed as Slices through a 2D Lattice

Yoon, K. J., Lewallen, S., Kinkhabwala, A. A., Tank, D. W. & Fiete, I. R., Mar 2 2016, In : Neuron. 89, 5, p. 1086-1099 14 p.

Research output: Contribution to journalArticle

Grid Cells
73 Citations (Scopus)

Recurrent Network Models of Sequence Generation and Memory

Rajan, K., Harvey, CD. D. & Tank, D. W., Apr 6 2016, In : Neuron. 90, 1, p. 128-142 15 p.

Research output: Contribution to journalArticle

Short-Term Memory
Parietal Lobe
Decision Making
Learning
Neurons
2015
7 Citations (Scopus)

A single-compartment model of calcium dynamics in nerve terminals and dendrites

Helmchen, F. & Tank, D. W., Jan 1 2015, In : Cold Spring Harbor Protocols. 2015, 2, p. 155-167 13 p.

Research output: Contribution to journalArticle

Dendrites
Calcium
Synaptic Vesicles
Neurons
Recycling
27 Citations (Scopus)

Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats

Scott, B. B., Constantinople, C. M., Erlich, J. C., Tank, D. W. & Brody, C. D., Dec 17 2015, In : eLife. 4, DECEMBER2015, e11308.

Research output: Contribution to journalArticle

Noise
Rats
Head
Signal detection
Decision making
70 Citations (Scopus)

The BRAIN initiative: Developing technology to catalyse neuroscience discovery

Jorgenson, L. A., Newsome, W., Anderson, D. J., Bargmann, C. I., Brown, E. N., Deisseroth, K., Donoghue, J. P., Hudson, K. L., Ling, G. S. F., Macleish, P. R., Marder, E., Normann, R. A., Sanes, J. R., Schnitzer, M. J., Sejnowski, T. J., Tank, D. W., Tsien, R. Y., Ugurbil, K. & Wingfield, J. C., May 19 2015, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 370, 1668, 20140164.

Research output: Contribution to journalArticle

neurophysiology
Neurosciences
Brain
Technology
brain
2014
31 Citations (Scopus)
Entorhinal Cortex
Prefrontal Cortex
Photons
Brain
Automatic Data Processing
76 Citations (Scopus)

Engagement of Neural Circuits Underlying 2D Spatial Navigation in a Rodent Virtual Reality System

Aronov, D. & Tank, D. W., Oct 22 2014, In : Neuron. 84, 2, p. 442-456 15 p.

Research output: Contribution to journalArticle

User-Computer Interface
Rodentia
Head
Electrophysiology
Walking
9 Citations (Scopus)

Prolonged, Brain-wide expression of nuclear-localized GCaMP3 for functional circuit mapping

Kim, C. K., Miri, A., Leung, L. C., Berndt, A., Mourrain, P., Tank, D. W. & Burdine, R. D., Nov 26 2014, In : Frontiers in neural circuits. 8, NOV, 138.

Research output: Contribution to journalArticle

Zebrafish
Brain
Fertilization
Fluorescence
Calcium
139 Citations (Scopus)

Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields

Rickgauer, J. P., Deisseroth, K. & Tank, D. W., Jan 1 2014, In : Nature Neuroscience. 17, 12, p. 1816-1824 9 p.

Research output: Contribution to journalArticle

Optical Imaging
Neurons
Optogenetics
Photons
Cell Communication
9 Citations (Scopus)

Two-photon imaging of neural activity in awake mobile mice

Dombeck, D. & Tank, D. W., Jul 1 2014, In : Cold Spring Harbor Protocols. 2014, 7, p. 726-736 11 p.

Research output: Contribution to journalArticle

Photons
Brain
Imaging techniques
Exercise equipment
Animal Behavior
2013
26 Citations (Scopus)

A Modeling Framework for Deriving the Structural and Functional Architecture of a Short-Term Memory Microcircuit

Fisher, D., Olasagasti, I., Tank, D. W., Aksay, E. R. F. & Goldman, M. S., Sep 4 2013, In : Neuron. 79, 5, p. 987-1000 14 p.

Research output: Contribution to journalArticle

Short-Term Memory
Neurons
40 Citations (Scopus)

Cellular Resolution Functional Imaging in Behaving Rats Using Voluntary Head Restraint

Scott, B. B., Brody, C. D. & Tank, D. W., Oct 16 2013, In : Neuron. 80, 2, p. 371-384 14 p.

Research output: Contribution to journalArticle

Operant Conditioning
Head
Photons
Rodentia
Fluorescence
177 Citations (Scopus)

Membrane potential dynamics of grid cells

Domnisoru, C., Kinkhabwala, A. A. & Tank, D. W., Mar 14 2013, In : Nature. 495, 7440, p. 199-204 6 p.

Research output: Contribution to journalArticle

Membrane Potentials
Architectural Accessibility
Patch-Clamp Techniques
Running
Grid Cells
2012
367 Citations (Scopus)

Choice-specific sequences in parietal cortex during a virtual-navigation decision task

Harvey, C. D., Coen, P. & Tank, D. W., Apr 5 2012, In : Nature. 484, 7392, p. 62-68 7 p.

Research output: Contribution to journalArticle

Parietal Lobe
Neurons
Short-Term Memory
Population
18 Citations (Scopus)

The synthesis-diffusion-degradation model explains Bicoid gradient formation in unfertilized eggs

Drocco, J. A., Wieschaus, E. F. & Tank, D. W., Oct 1 2012, In : Physical Biology. 9, 5, 055004.

Research output: Contribution to journalArticle

Ovum
Zygote
Drosophila melanogaster
Cell Nucleus Division
Photons
57 Citations (Scopus)

Widespread state-dependent shifts in cerebellar activity in locomoting mice

Ozden, I., Dombeck, D. A., Hoogland, T. M., Tank, D. W. & Wang, S. S-H., Aug 3 2012, In : PloS one. 7, 8, e42650.

Research output: Contribution to journalArticle

Purkinje Cells
Dendrites
Interneurons
Fibers
mice
2011
40 Citations (Scopus)

Measurement and perturbation of morphogen lifetime: Effects on gradient shape

Drocco, J. A., Grimm, O., Tank, D. W. & Wieschaus, E. F., Oct 19 2011, In : Biophysical Journal. 101, 8, p. 1807-1815 9 p.

Research output: Contribution to journalArticle

Proteins
Biological Phenomena
Drosophila
Embryonic Development
Theoretical Models
58 Citations (Scopus)

Regression-based identification of behavior-encoding neurons during large-scale optical imaging of neural activity at cellular resolution

Miri, A., Daie, K., Burdine, R. D., Aksay, E. & Tank, D. W., Feb 1 2011, In : Journal of Neurophysiology. 105, 2, p. 964-980 17 p.

Research output: Contribution to journalArticle

Optical Imaging
Neurons
Calcium
Rhombencephalon
Laser Therapy
67 Citations (Scopus)

Spatial gradients and multidimensional dynamics in a neural integrator circuit

Miri, A., Daie, K., Arrenberg, A. B., Baier, H., Aksay, E. & Tank, D. W., Sep 1 2011, In : Nature Neuroscience. 14, 9, p. 1150-1161 12 p.

Research output: Contribution to journalArticle

Neurons
Zebrafish
Larva
Population
2010
362 Citations (Scopus)

Functional imaging of hippocampal place cells at cellular resolution during virtual navigation

Dombeck, D. A., Harvey, C. D., Tian, L., Looger, L. L. & Tank, D. W., Nov 1 2010, In : Nature neuroscience. 13, 11, p. 1433-1440 8 p.

Research output: Contribution to journalArticle

Spatial Behavior
User-Computer Interface
Neurons
Photons
Cognition
2009
111 Citations (Scopus)

Functional clustering of neurons in motor cortex determined by cellular resolution imaging in awake behaving mice

Dombeck, D. A., Graziano, M. S. & Tank, D. W., Nov 4 2009, In : Journal of Neuroscience. 29, 44, p. 13751-13760 10 p.

Research output: Contribution to journalArticle

Motor Cortex
Cluster Analysis
Neurons
Grooming
Forelimb
469 Citations (Scopus)

Intracellular dynamics of hippocampal place cells during virtual navigation

Harvey, C. D., Collman, F., Dombeck, D. A. & Tank, D. W., Oct 15 2009, In : Nature. 461, 7266, p. 941-946 6 p.

Research output: Contribution to journalArticle

User-Computer Interface
Patch-Clamp Techniques
Spatial Behavior
Theta Rhythm
Architectural Accessibility
32 Citations (Scopus)

Pseudorabies virus infection alters neuronal activity and connectivity in vitro

McCarthy, K. M., Tank, D. W. & Enquist, L. W., Oct 1 2009, In : PLoS Pathogens. 5, 10, e1000640.

Research output: Contribution to journalArticle

Suid Herpesvirus 1
Virus Diseases
Action Potentials
Neurons
Infection
162 Citations (Scopus)

Two-photon excitation of channelrhodopsin-2 at saturation

Rickgauer, J. P. & Tank, D. W., Sep 1 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 35, p. 15025-15030 6 p.

Research output: Contribution to journalArticle

Photons
Light
Ion Channels
Action Potentials
Neurons
2008
17 Citations (Scopus)

Rate-specific synchrony: Using noisy oscillations to detect equally active neurons

Markowitz, D. A., Collman, F., Brody, C. D., Hopfield, J. J. & Tank, D. W., Jun 17 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 24, p. 8422-8427 6 p.

Research output: Contribution to journalArticle

Neurons
Brain
Dermatoglyphics
Population
Action Potentials
102 Citations (Scopus)

Spatiotemporally graded NMDA spike/plateau potentials in basal dendrites of neocortical pyramidal neurons

Major, G., Polsky, A., Denk, W., Schiller, J. & Tank, D. W., May 1 2008, In : Journal of neurophysiology. 99, 5, p. 2584-2601 18 p.

Research output: Contribution to journalArticle

Pyramidal Cells
N-Methylaspartate
Dendrites
Action Potentials
Glutamic Acid
2007
69 Citations (Scopus)

Functional dissection of circuitry in a neural integrator

Aksay, E., Olasagasti, I., Mensh, B. D., Baker, R., Goldman, M. S. & Tank, D. W., Apr 1 2007, In : Nature Neuroscience. 10, 4, p. 494-504 11 p.

Research output: Contribution to journalArticle

Dissection
Population
Goldfish
Population Dynamics
Short-Term Memory
565 Citations (Scopus)

Imaging Large-Scale Neural Activity with Cellular Resolution in Awake, Mobile Mice

Dombeck, D. A., Khabbaz, A. N., Collman, F., Adelman, T. L. & Tank, D. W., Oct 4 2007, In : Neuron. 56, 1, p. 43-57 15 p.

Research output: Contribution to journalArticle

Head
Photons
Optical Imaging
Running
Artifacts
399 Citations (Scopus)

Probing the Limits to Positional Information

Gregor, T., Tank, D. W., Wieschaus, E. F. & Bialek, W., Jul 13 2007, In : Cell. 130, 1, p. 153-164 12 p.

Research output: Contribution to journalArticle

Embryonic Structures
Molecules
Chemical activation
Drosophila
Noise
315 Citations (Scopus)

Stability and Nuclear Dynamics of the Bicoid Morphogen Gradient

Gregor, T., Wieschaus, E. F., McGregor, A. P., Bialek, W. & Tank, D. W., Jul 13 2007, In : Cell. 130, 1, p. 141-152 12 p.

Research output: Contribution to journalArticle

Interphase
Photobleaching
Optical Imaging
Mitosis
Fertilization
2005
201 Citations (Scopus)

Diffusion and scaling during early embryonic pattern formation

Gregor, T., Bialek, W., De Ruyter Van Steveninck, R. R., Tank, D. W. & Wieschaus, E. F., Dec 20 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 51, p. 18403-18407 5 p.

Research output: Contribution to journalArticle

Body Patterning
Embryonic Structures
Gene Expression
Ovum
Drosophila
2004
31 Citations (Scopus)

Plasticity and tuning by visual feedback of the stability of a neural integrator

Major, G., Baker, R., Aksay, E., Mensh, B., Seung, H. S. & Tank, D. W., May 18 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 20, p. 7739-7744 6 p.

Research output: Contribution to journalArticle

Sensory Feedback
Homeless Youth
Head Movements
Goldfish
Brain
18 Citations (Scopus)

Plasticity and tuning of the time course of analog persistent firing in a neural integrator

Major, G., Baker, R., Aksay, E., Seung, H. S. & Tank, D. W., May 18 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 20, p. 7745-7750 6 p.

Research output: Contribution to journalArticle

Sensory Feedback
Neurons
Goldfish
Brain Stem
History
90 Citations (Scopus)

Quantifying the ontogeny of optokinetic and vestibuloocular behaviors in zebrafish, medaka, and goldfish

Beck, J. C., Gilland, E., Tank, D. W. & Baker, R., Dec 1 2004, In : Journal of Neurophysiology. 92, 6, p. 3546-3561 16 p.

Research output: Contribution to journalArticle

Oryzias
Goldfish
Zebrafish
Fishes
Vestibulo-Ocular Reflex
34 Citations (Scopus)

Spontaneous eye movements in goldfish: Oculomotor integrator performance, plasticity, and dependence on visual feedback

Mensh, B. D., Aksay, E., Lee, D. D., Seung, H. S. & Tank, D. W., Jan 1 2004, In : Vision Research. 44, 7, p. 711-726 16 p.

Research output: Contribution to journalArticle

Sensory Feedback
Goldfish
Darkness
Eye Movements
Light
2003
33 Citations (Scopus)

Correlated Discharge among Cell Pairs within the Oculomotor Horizontal Velocity-to-Position Integrator

Aksay, E., Baker, R., Seung, H. S. & Tank, D. W., Nov 26 2003, In : Journal of Neuroscience. 23, 34, p. 10852-10858 7 p.

Research output: Contribution to journalArticle

Neurons
Brain Stem
Goldfish
Inhibition (Psychology)
16 Citations (Scopus)

History Dependence of Rate Covariation between Neurons during Persistent Activity in an Oculomotor Integrator

Aksay, E., Major, G., Goldman, M. S., Baker, R., Seung, H. S. & Tank, D. W., Nov 1 2003, In : Cerebral Cortex. 13, 11, p. 1173-1184 12 p.

Research output: Contribution to journalArticle

History
Neurons
Rhombencephalon
Goldfish
Saccades
118 Citations (Scopus)

Robust Persistent Neural Activity in a Model Integrator with Multiple Hysteretic Dendrites per Neuron

Goldman, M. S., Levine, J. H., Major, G., Tank, D. W. & Seung, H. S., Nov 1 2003, In : Cerebral Cortex. 13, 11, p. 1185-1195 11 p.

Research output: Contribution to journalArticle

Dendrites
Neurons
Short-Term Memory
Vestibulo-Ocular Reflex
Saccades
2002
51 Citations (Scopus)

Enhanced two-photon excitation through optical fiber by single-mode propagation in a large core

Helmchen, F., Tank, D. W. & Denk, W., May 20 2002, In : Applied Optics. 41, 15, p. 2930-2934 5 p.

Research output: Contribution to journalArticle

propagation modes
Optical fibers
Photons
optical fibers
fibers
30 Citations (Scopus)

Linear regression of eye velocity on eye position and head velocity suggests a common oculomotor neural integrator

Goldman, M. S., Kaneko, C. R. S., Major, G., Aksay, E., Tank, D. W. & Seung, H. S., Aug 23 2002, In : Journal of Neurophysiology. 88, 2, p. 659-665 7 p.

Research output: Contribution to journalArticle

Vestibulo-Ocular Reflex
Linear Models
Head
Saccades
Head Movements